Results 251 to 260 of about 10,060,126 (337)

An outcome evaluation of the maternal care manual of the Perinatal Education Programme (PEP)

, 2008
Alfeous Rundare
openalex   +1 more source

Predictors of early graft outcome in liver transplantation [PDF]

, 1996
, JR Doyle HR, Aldrighetti, L, Doria, C, Gayowski, TJP, Madariaga,, Marino, IR, Morelli, F, Starzl, TE   +7 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Characteristics of mental health awareness programmes for workplace well-being in low-income and middle-income countries: a scoping review. [PDF]

BMJ Public Health
Luberenga I, Kasujja R, Vasanthan LT, Dwanyen L, Sanghvi A, Joseph L.   +5 more
europepmc   +1 more source

'Brisas Del Mar': Judicial and Political Outcomes of the Cuban Rafter Crisis in Guantánamo

, 2012
Christina M. Frohock
openalex   +1 more source

Predicting community-acquired pneumonia outcome using time series data and machine learning [PDF]

Daniel Lozano-Rojas, Matthew Richardson, Gerrit Woltmann, Robert C. Free   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Development of a Modified Textbook Outcome in Evaluating Robot-Assisted Middle Pancreatectomy: A Real-World Study of RMP Surgery in a High-Volume Pancreatic Disease Center. [PDF]

Cancer Med
Li J, Qian L, Xu Z, Wang X, Xu W, Deng X, Peng C, Shen B, Shi Y.   +8 more
europepmc   +1 more source

A critical analysis of Pradhan Mantri Awas Yojana: A study on its implementation and outcomes in North 24 Parganas [PDF]

CMA Himadri Halder, Saurav Ghosh, Jyotirmoy Koley   +2 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source