Results 281 to 290 of about 14,055,650 (415)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

CMRI-detected brain injuries and clinical key risk factors associated with adverse neurodevelopmental outcomes in very preterm infants. [PDF]

Sci Rep
Drommelschmidt K, Mayrhofer T, Müller H, Foldyna B, Raudzus J, Göricke SL, Schweiger B, Sirin S.   +7 more
europepmc   +1 more source

Influence of Pregnancy Spacing on Outcome of Pregnancy [PDF]

, 1973
Jean Fedrick, Philippa Adelstein
openalex   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

A roadmap for genome projects to foster psychosocial and economic evidence to further policy and practice. [PDF]

Commun Med (Lond)
Chung CCY, Chu ATW, Chung BHY.
europepmc   +1 more source

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort.

The Lancet Diabetes and Endocrinology, 2017
T. Williams, J. Lenders, P. Mulatero, J. Burrello, M. Rottenkolber, C. Adolf, F. Satoh, L. Amar, M. Quinkler, J. Deinum, F. Beuschlein, K. K. Kitamoto, U. Pham, R. Morimoto, H. Umakoshi, A. Prejbisz, T. Kocjan, M. Naruse, M. Stowasser, T. Nishikawa, W. Young, C. Gomez-Sanchez, J. Funder, M. Reincke   +23 more
semanticscholar   +1 more source

Improving Treatment Outcome for Children with HIV [PDF]

, 2011
Calmy, Alexandra L, Ford, Nathan
core   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Effectiveness of obesity interventions in sub-Saharan Africa: A systematic review and meta-analyses. [PDF]

PLoS One
Agyemang K, Crankson S, Anokye N.
europepmc   +1 more source

Avaliação da qualidade de vida em pacientes com hanseníase: uso do Medical Outcomes Study 36

, 1969
David Lopes Neto, Rogério Olmedija de Araújo, Mayara Elisa Freire Meneghini, Lucila Midori Tsuzuki   +3 more
openalex   +2 more sources