Results 71 to 80 of about 14,941,622 (355)

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Long‐Term Effects of Intensive Lifestyle Intervention on Cardiometabolic Outcomes in Patients With Diabetes in Real‐World Clinical Practice: A 15‐Year Longitudinal Study

Journal of Diabetes
Introduction We previously demonstrated that achieving and maintaining ≥ 7% weight loss at 1 year in patients with diabetes (DM), through multidisciplinary intensive lifestyle intervention (ILI) in real‐world clinical practice, predicts improvement in ...
Abdelrahman Khater, Marwa Al‐Badri, Tareq Salah, Shilton E. Dhaver, Karim Kibaa, Osama Hamdy   +5 more
doaj   +1 more source

Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

Nature, 2011
Oestrogen receptor-α (ER) is the defining and driving transcription factor in the majority of breast cancers and its target genes dictate cell growth and endocrine response, yet genomic understanding of ER function has been restricted to model systems ...
R. Stark
semanticscholar   +1 more source

A Statistical Model for Stroke Outcome Prediction and Treatment Planning

, 2016
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit, Rajan, Vaibhav, Sarma, G R K, Sengupta, Abhishek   +3 more
core   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Extent of hypoattenuation on CT angiography source images in Basilar Artery occlusion: prognostic value in the Basilar Artery International Cooperation Study [PDF]

, 2011
<p><b>Background and Purpose:</b> The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) quantifies the extent of early ischemic changes in the posterior circulation with a 10-point grading system.
Algra, Ale, Basilar Artery International Cooperation Study Group,, Demchuk, Andrew M., Dzialowski, Imanuel, Engelter, Stefan T., Hill, Michael D., Kappelle, L. Jaap, Khomenko, Andrei, Mattle, Heinrich P., Michel, Patrik, Muir, Keith W., Pfefferkorn, Thomas, Puetz, Volker, Schonewille, Wouter J., Szabo, Kristina, Tanne, David, von Kummer, Ruediger, Weimar, Christian, Wijman, Christine A. C.   +18 more
core   +1 more source

Prognostic significance of short-term blood pressure variability in acute stroke [PDF]

, 2015
Background and Purpose— Blood pressure variability (BPV) may be an important prognostic factor acutely after stroke. This review investigated the existing evidence for the effect of BPV on outcome after stroke, also considering ...
Manning, Lisa S., Potter, John F., Robinson, Thompson G., Rothwell, Peter M.   +3 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Domestic violence in South Australia: a population survey of males and females

Australian and New Zealand Journal of Public Health, 2003
Objective: To determine the self‐reported prevalence of domestic violence in South Australian adults and to examine the associated risk factors, demographic factors and related health issues using computer‐aided telephone interviewing (CATI) methodology.
Eleonora Dal Grande, Jacqueline Hickling, Anne Taylor, Tony Woollacott   +3 more
doaj   +1 more source