Results 81 to 90 of about 14,971,001 (334)

Patient-Reported Outcome (PRO) Consortium translation process: consensus development of updated best practices

Journal of Patient-Reported Outcomes, 2018
This paper describes the rationale and goals of the Patient-Reported Outcome (PRO) Consortium’s instrument translation process. The PRO Consortium has developed a number of novel PRO measures which are in the process of qualification by the U.S. Food and
Sonya Eremenco, Sheryl Pease, Sarah Mann, Pamela Berry, on behalf of the PRO Consortium’s Process Subcommittee   +4 more
doaj   +1 more source

Clients’ experiences on North America’s first take-home injectable opioid agonist treatment (iOAT) program: a qualitative study

BMC Health Services Research, 2023
Background To support public health measures during the COVID-19 pandemic, oral opioid agonist treatment (OAT) take-home doses were expanded in Western countries with positive results. Injectable OAT (iOAT) take-home doses were previously not an eligible
Eugenia Oviedo-Joekes, Sophia Dobischok, José Carvajal, Scott MacDonald, Cheryl McDermid, Piotr Klakowicz, Scott Harrison, Julie LaJeunesse, Nancy Chow, Murray Brown, Sam Gill, Martin Schechter   +11 more
doaj   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Increasing gaps in health inequalities related to non-communicable diseases in South Australia; implications towards behavioural risk factor surveillance systems to provide evidence for action

BMC Public Health, 2019
Background Although Australia is a country cited as having generally low health inequalities among different socioeconomic groups, inequalities have persisted. The aim of this analysis was to highlight how inequalities have evolved over a 13 years period
Stefano Campostrini, Eleonora Dal Grande, Anne W. Taylor   +2 more
doaj   +1 more source

Outcome-based pricing for new pharmaceuticals via rebates [PDF]

, 2020
The price of new brand-name prescription drugs has been rising fast in the United States. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year.
Adida, E
core  

Demonstration project on epilepsy in Brazil - Outcome assessment [PDF]

, 2007
Purpose: To assess the outcome of patients with epilepsy treated at primary care health units under the framework of the demonstration project on epilepsy in Brazil, part of the WHO/ILAE/IBE Global Campaign Against Epilepsy. Method.
Borges, K, Borges, MA, Cendes, F, de Boer, HM, Espiindola, J, Fernandes, PT, Guerreiro, CAM, Li, LM, Marques, LHN, Miranda, CT, Noronha, ALA, Prilipko, L, Sander, JW, Zanetta, DMT   +13 more
core   +1 more source

How to select outcome measurement instruments for outcomes included in a “Core Outcome Set” – a practical guideline

Trials, 2016
BackgroundIn cooperation with the Core Outcome Measures in Effectiveness Trials (COMET) initiative, the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) initiative aimed to develop a guideline on how to select ...
C. Prinsen, S. Vohra, M. Rose, M. Boers, P. Tugwell, M. Clarke, P. Williamson, C. Terwee   +7 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Abiraterone acetate and docetaxel with androgen deprivation therapy in high-volume metastatic hormone-sensitive prostate cancer in China: an indirect treatment comparison and cost analysis

Cost Effectiveness and Resource Allocation, 2019
Background To conduct an indirect treatment comparison of patients with high-volume mHSPC and a cost analysis between Abi-ADT and Doc-ADT therapies in China. Methods The Bucher technique for indirect treatment comparison was used.
Xin Hu, Shuli Qu, Xingxing Yao, Chaoyun Li, Yanjun Liu, Jianye Wang   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source