Results 81 to 90 of about 549,867 (276)

Implementing an aim-based outcome measure in a psychoanalytic child psychotherapy service: Insights, experiences and evidence

, 2014
In this paper, we describe the use of an aim-based outcome measure used in routine outcome monitoring of child and adolescent psychotherapy within a child and adolescent mental health service. We present empirical evidence drawn from a cohort of 34 child
Helen Muller, Emanuel, R, Catty, Jocelyn, Anscombe, Elizabeth, Muller, Helen, Emanuel, Ricky, Cantle, Alison, Anscombe, E, Cantle, A, Catty, J, Ricky Emanuel, Muller, H, Jocelyn Catty, Elizabeth Anscombe, Alison Cantle   +14 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Study protocol: national research partnership to improve primary health care performance and outcomes for Indigenous peoples

, 2010
Background Strengthening primary health care is critical to reducing health inequity between Indigenous and non-Indigenous Australians. The Audit and Best practice for Chronic Disease Extension (ABCDE) project has facilitated the implementation of modern
Weston, R., Grogan Haylene, Semmens, James, Thompson, Sandra, Leon Dallas, McDermott, R, Burke, Hugh, Leon, D, Anderson, Ian, Nagel Tricia, Moore, E, Burke, H., Si Damin, Semmens James, Shannon, C, Grogan, H, Semmens, J., Thompson Sandra, Stanley, A., Gardner Karen, Anderson, I., Weeramanthri, Tarun, Weston, Richard, McDermott Robyn, Si, D., Leon, D., Grogan, H., Weeramanthri, T., Rowley, Kevin, Scrimgeour, DJ, Stanley, A, Nagel, T, Scrimgeour, David, Nagel, Tricia, Leon, Dallas, Rowley Kevin, Connors, C., Scrimgeour David J, Bailie, R., Nagel, T., Grogan, Haylene, McDermott, R., Gardner, Karen, Rowley, K., Anderson Ian, Stanley Andrew, Shannon, C., Si, Damin, Scrimgeour, D., McDermott, Robyn, Weston Richard, Connors, C, Rowley, K, Connors Christine, Shannon Cindy, Si, D, Burke, H, Weeramanthri, T, Moore, Elizabeth, Burke Hugh, Anderson, I, Bailie, R, Thompson, S., Scrimgeour, David J., Moore, E., Bailie, Ross, Semmens, J, Weeramanthri Tarun, Moore Elizabeth, Connors, Christine, Gardner, K, Bailie Ross, Gardner, K., Weston, R, Thompson, S, Shannon, Cindy, Stanley, Andrew   +76 more
core   +1 more source

Improving the outcomes of primary care attenders with common mental disorders in developing countries: a cluster randomized controlled trial of a collaborative stepped care intervention in Goa, India [PDF]

, 2008
Background and Objective: Common mental disorders (CMD) are a leading global burden of disease. Up to 30% of primary care attenders suffer from these disorders but most do not receive evidence-based drug or psychological treatments.
Ricardo Araya, Simon, G, Gregory Simon, Chisholm, D, Weiss, H, Sulochana Pednekar, Weiss Helen, Pednekar, S, Chisholm, Daniel, Kirkwood, BR, Daniel Chisholm, Helen Weiss, Patel Vikram H, Simon, Gregory, Weiss, Helen, Araya Ricardo, King, M, Pednekar, Sulochana, Simon Gregory, Chisholm Daniel, Araya, Ricardo, Araya, R, Kirkwood Betty R, Betty R Kirkwood, Kirkwood, Betty R, King, Michael, Patel, VH, King Michael, Michael King, Patel, Vikram H, Vikram H Patel, Pednekar Sulochana   +31 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Avaliação da qualidade de assistência primária à saúde em localidade urbana da região sul do Brasil

Revista de Saúde Pública
Foi estudada transversalmente uma amostra de 10% dos pacientes que consultaram em dois Postos de Assistência Primária à Saúde da Cidade de Pelotas (RS), Brasil, com o objetivo de avaliar, qualitativamente, o cuidado à saúde que estava sendo oferecido ...
Iná S. Halal, Felipe Sparrenberger, Anete M. Bertoni, Carla Ciacomet, Carlos E. Seibel, Flávia M. Lahude, Gilson A. Magalhães, Lirio Barreto, Rita C.A. Lira   +8 more
doaj  

A scoping review on implementation processes and outcomes of models of care for low back pain in primary healthcare

BMC Health Services Research
Background To address the societal burden of low back pain (LBP), several health systems have adopted Models of Care (MoCs). These evidence-informed models aim for consistent care and outcomes.
Susana Tinoco Duarte, Alexandre Moniz, Daniela Costa, Helena Donato, Bruno Heleno, Pedro Aguiar, Eduardo B Cruz   +6 more
doaj   +1 more source

Triumph of hope over experience: learning from interventions to reduce avoidable hospital admissions identified through an Academic Health and Social Care Network

BMC Health Services Research, 2012
Background Internationally health services are facing increasing demands due to new and more expensive health technologies and treatments, coupled with the needs of an ageing population.
Woodhams Victoria, de Lusignan Simon, Mughal Shakeel, Head Graham, Debar Safia, Desombre Terry, Hilton Sean, Al Sharifi Houda   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Availability of Periodontal Instruments, Procedures, and Specialized Referral in Primary Health Care in Brazil

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To analyze the availability of periodontal instruments, services, and specialized referrals in Primary Health Care and compare Brazilian geographical regions.
Manoelito Ferreira Silva-Junior, Elisa Aparecida da Silva Freitas, Fabiana Ribeiro Marques, Mabelle de Freitas Monteiro, Marcia Helena Baldani   +4 more
doaj