Results 101 to 110 of about 797,426 (292)

Pressure ulcers and Charcot's definitions: report on two cases

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Pressure ulcers are lesions caused by inadequate blood flow and tissue malnourishment secondary to prolonged pressure on skin, soft connective tissues, muscle and/or bones.
Hélio Afonso Ghizoni Teive, Ricardo William Genaro Rodrigues de Campos, Renato Puppi Munhoz, Lineu César Werneck   +3 more
doaj   +1 more source

Application of Process Portofolio Assessment Based on Guided Inquiry Model in Improving Critical Thinking Skills and Learning Outcomes of Science Education Students

, 2023
Ummiy Fauziyah Laili, Zakiyatus Soimah, Atika Anggraini, Sayyidah Auliayur Rohmah, Rahmawati Yanita Sari   +4 more
openalex   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Fontan Circulation of the Next Generation: Why It's Necessary, What it Might Look Like

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Shelby Kutty, Marshall L. Jacobs, W. Reid Thompson, David A. Danford   +3 more
doaj   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Las unidades de hemodiálisis en México: una evaluación de sus características, procesos y resultados An evaluation of the characteristics, processes and outcomes of hemodialysis units in Mexico

Salud Pública de México, 2011
OBJETIVO. Evaluar las características, procesos y resultados, así como, la estructura de una muestra de unidades de hemodiálisis (UH) en México. Material y métodos. Estudio transversal en 83 UH públicas y privadas del país.
Laura Leticia Tirado-Gómez, Juan Luis Durán-Arenas, Mario Enrique Rojas-Russell, Aída Venado-Estrada, Reyna Lizzete Pacheco-Domínguez, Malaquías López-Cervantes   +5 more
doaj  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Impacto de un programa de atención domiciliaria al enfermo crónico en ancianos: calidad de vida y reingresos hospitalarios Impact of the program home care for the chronically ill for elderly: quality of life and hospital readmissions

Salud Pública de México, 2011
OBJETIVO: Evaluar el impacto del programa Atención Domiciliaria al Enfermo Crónico (ADEC) comparado con la atención habitual (AH) a ancianos con dependencia funcional, derechohabientes del Instituto Mexicano del Seguro Social (IMSS).
María Claudia Espinel-Bermúdez, Sergio Sánchez-García, Teresa Juárez-Cedillo, José Juan García-González, Álvaro Viveros-Pérez, Carmen García-Peña   +5 more
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source