Results 121 to 130 of about 2,144,741 (288)

Disparities in the protagonism of oral health teams in the work process of Primary Healthcare [PDF]

Revista de Saúde Pública
OBJECTIVE Evaluate and compare the protagonism of Oral Health teams (OHt) in the teamwork process in Primary Healthcare (PHC) over five years and estimate the magnitude of disparities between Brazilian macro-regions. METHODS Ecological study that used
Érika Talita Silva, Raquel Conceição Ferreira, Fabiano Costa Diniz, Milena Ribeiro Gomes, Andréa Maria Eleutério de Barros Lima Martins, Loliza Luiz Figueiredo Houri Chalub, Maria Inês Barreiros Senna   +6 more
doaj   +1 more source

Assessment of mental and physical health outcomes over time in an integrated care setting

BMC Primary Care
Integrated care addresses the fragmentation of patient health services and potentially improves the experience of care, reduces healthcare costs, and improves health outcomes. This study assessed the improvements in mental health and physical health outcomes among patients living with mental health challenges and treated in an integrated care setting ...
Dependra Bhatta, Monteic A. Sizer, Binod Acharya, Dipendra Banjara   +3 more
openaire   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Modeling Zero-inflated Count Data Using Generalized Poisson and Ordinal Logistic Regression Models in Medical Research

Oman Medical Journal
Objectives: In medical research, the study’s design and statistical methods are pivotal, as they guide interpretation and conclusion. Selecting appropriate statistical models hinges on the distribution of the outcome measure.
Bijesh Yadav, Lakshmanan Jeyaseelan, Marimuthu Sappani, Thenmozhi Mani, Sebastian George, Shrikant I. Bangdiwala   +5 more
doaj   +1 more source

Clinical outcomes of 11,436 kidney transplants performed in a single center - Hospital do Rim

Brazilian Journal of Nephrology, 2017
Introduction: Kidney transplantation is considered a cost-effective treatment compared to dialysis but accounts for a significant percentage of the public health care resources. Therefore, efficient systems capable of performing high number of procedures
José Medina Pestana
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Effect of Preventive Primary Care Outreach on Health Related Quality of Life Among Older Adults at Risk of Functional Decline: Randomised Controlled Trial [PDF]

, 2010
Objective: To evaluate the impact of a provider initiated primary care outreach intervention compared with usual care among older adults at risk of functional decline. Design: Randomised controlled trial.
Brazil, Kevin, Furlong, William, Goldsmith, Charles H., Guthrie, Dawn M., Hutchison, Brian, Kaczorowski, Janusz, Ploeg, Jenny   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Role of the Health Care Sector in Expanding Economic Opportunity [PDF]

, 2007
This report provides an overview and critical assessment of the ways in which multinational pharmaceutical companies currently participate in expanding economic opportunities in developing countries.
Adeeb Mahmud, Marcie Parkhurst
core