Results 141 to 150 of about 2,109,315 (306)

Availability of Periodontal Instruments, Procedures, and Specialized Referral in Primary Health Care in Brazil

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To analyze the availability of periodontal instruments, services, and specialized referrals in Primary Health Care and compare Brazilian geographical regions.
Manoelito Ferreira Silva-Junior, Elisa Aparecida da Silva Freitas, Fabiana Ribeiro Marques, Mabelle de Freitas Monteiro, Marcia Helena Baldani   +4 more
doaj  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Linking health and social data to assess care needs and outcomes: Czech experience

European Journal of Public Health
Abstract Background Effective management of health and social care services requires comprehensive and timely data. Czechia has linked its National Health Information System (NHIS) and National Social Information System (NSIS), creating an integrated dataset for evaluation of provided health ...
Benešová, K, Jarkovsk’, J, Kubát, J, Klimeš, D, Soukupová, J, Činčila, B, Petruželka, B, Mužík, J, Dušek, L   +8 more
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Avaliação da qualidade de assistência primária à saúde em localidade urbana da região sul do Brasil

Revista de Saúde Pública
Foi estudada transversalmente uma amostra de 10% dos pacientes que consultaram em dois Postos de Assistência Primária à Saúde da Cidade de Pelotas (RS), Brasil, com o objetivo de avaliar, qualitativamente, o cuidado à saúde que estava sendo oferecido ...
Iná S. Halal, Felipe Sparrenberger, Anete M. Bertoni, Carla Ciacomet, Carlos E. Seibel, Flávia M. Lahude, Gilson A. Magalhães, Lirio Barreto, Rita C.A. Lira   +8 more
doaj  

Health Care Assessment of Health Care Delivery and Outcome- A West African Review

Saudi Journal of Medicine, 2019
Lydia T. Cassell, Ayun K. Cassell
openaire   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Stress hyperglycemia ratio and albumin predict in-hospital outcomes in patients with acute myocardial infarction: a cohort study

Scientific Reports
Elevated stress hyperglycemia ratio (SHR) is a putative risk indicator for acute myocardial infarction (AMI). However, the relationship between SHR, albumin, and subsequent cardiovascular adverse outcomes is less well-established.
Yuxiu Yang, Fei Gao, Xiaoteng Ma, Lixia Yang, Zhijian Wang, Yujie Zhou   +5 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source