Results 91 to 100 of about 918,364 (316)

Can the shift from needs-led to outcomes-focused assessment in health and social care deliver on policy priorities?

, 2010
Assessment, planning and review are at the heart of the provision of services and support in health and social care in the community, providing key means through which professionals interact with people using their services.
Miller, Emma
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Fatores associados à percepção de melhora por usuários de Centros de Atenção Psicossocial do Sul do Brasil

Cadernos de Saúde Pública
Este estudo objetivou investigar os fatores associados à melhora percebida pelos usuários de Centros de Atenção Psicossocial (CAPS). Estudo transversal, realizado com 1.493 usuários de CAPS do Sul do Brasil.
Uiasser Thomas Franzmann, Luciane Prado Kantorski, Vanda Maria da Rosa Jardim, Carlos Alberto dos Santos Treichel, Michele Mandagará de Oliveira, Fabiane Machado Pavani   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The short-term effect on alliance and satisfaction of using patient feedback scales in mental health out-patient treatment. A randomised controlled trial

BMC Health Services Research, 2012
Background The main aim was to investigate the effect of using two brief feedback scales in mental health out-patient treatment six weeks after starting treatment, compared to treatment as usual.
Rise Marit, Eriksen Lasse, Grimstad Hilde, Steinsbekk Aslak   +3 more
doaj   +1 more source

Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA [PDF]

, 2009
<b>Background</b>: Foot and ankle problems are a common but relatively neglected manifestation of juvenile idiopathic arthritis. Studies of medical and non-medical interventions have shown that clinical outcome measures can be improved ...
Sturrock, R.D., Hendry Gordon J, McColl, John, Sturrock Roger D, Lorgelly Paula K, Woodburn Jim, Woodburn, J., McColl John, Sturrock, Roger, Gardner-Medwin, J., Gardner-Medwin Janet, Turner, Deborah E., Browne, Michael, Turner, Deborah, Browne Michael, Hendry, Gordon, Lorgelly, Paula K., Hendry, Gordon J., Lorgelly, Paula, Sturrock, Roger D., Woodburn, James, Watt Gordon F, Gardner-Medwin, Janet, Hendry, Gordon; id_orcid, Browne, M., Turner Deborah E, Friel, L., Turner, D.E., Watt, Gordon, Friel, Lorraine, Hendry, G.J., Friel Lorraine, McColl, J., Lorgelly, P., Watt, G.F., Watt, Gordon F.   +35 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Avaliação dos resultados de intervenção após mudanças realizadas nos cuidados peri-operatórios em pacientes submetidos a operações abdominais eletivas

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar os resultados da introdução de novas medidas visando acelerar a recuperação pós-operatória de pacientes submetidos à cirurgia abdominal eletiva.
Mayra da Rosa Martins Walczewski, Ariane Zanetta Justino, Eduardo André Bracci Walczewski, Tatiane Coan   +3 more
doaj   +1 more source

Prognostic value of urethral mobility and valsalva leak point pressure for female transobturator sling procedure

International Brazilian Journal of Urology, 2012
PURPOSE: To analyze the influence of urethral mobility and Valsalva leak point pressure on postoperative outcomes of transobturator sling (TOT) for female stress urinary incontinence. MATERIALS AND METHODS: A prospective cohort was conducted including 66
Luis Gustavo Morato de Toledo, Pedro Henrique Oliveira Cabral, Mário Luís Casella, Gabriel Elias Politi, Sandro Nasser Cardoso, Luiz Figueiredo Mello, Sidney Glina   +6 more
doaj   +1 more source

Understanding and Assessing the Therapeutic Relationship in Community Mental Health Care

, 2006
PhDThe clinician-patient relationship is at the core of community mental health care and impacts on outcome, but no instrument has been specifically developed for its assessmentE.
McGurie-Snieckus, Rebecca
core