Results 121 to 130 of about 918,364 (316)

Disparities in the protagonism of oral health teams in the work process of Primary Healthcare [PDF]

open access: yesRevista de Saúde Pública
OBJECTIVE Evaluate and compare the protagonism of Oral Health teams (OHt) in the teamwork process in Primary Healthcare (PHC) over five years and estimate the magnitude of disparities between Brazilian macro-regions. METHODS Ecological study that used
Érika Talita Silva   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Modeling Zero-inflated Count Data Using Generalized Poisson and Ordinal Logistic Regression Models in Medical Research

open access: yesOman Medical Journal
Objectives: In medical research, the study’s design and statistical methods are pivotal, as they guide interpretation and conclusion. Selecting appropriate statistical models hinges on the distribution of the outcome measure.
Bijesh Yadav   +5 more
doaj   +1 more source

The work of registered nurses and care assistants with older people in nursing homes: Can the outcomes be distinguished?

open access: yes, 2006
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The need for Registered Nurses (RNs) in the long-term care of older people is being questioned, particularly in the context of nursing shortages, while ...
Heath, Hazel
core  

Outcome prediction for patients with obstructive lung disease considered for admission to critical care units in England, Wales and Northern Ireland [PDF]

open access: yes
Objective. To develop an outcome prediction score for patients with obstructive lung disease considered for admission to critical care. Design. Prospective cohort study using multivariate logistic regression for model building
Wildman, Martin James
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Developing a model of occupational therapy practice for children with attention deficit hyperactivity disorder (ADHD)

open access: yes, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 15/06/2005.This three-stage study led to the development of a delineation model of occupational therapy practice for children with Attention Deficit ...
Chu, Sidney Kin Hoi
core  

Development of a minimum stroke dataset for electronic collection in routine stroke care [PDF]

open access: yes, 2011
Improving stroke care is a national priority and adherence to national policy and guidelines is closely monitored by numerous organisations using a considerable number of overlapping indicators of stroke care processes.
Teale, Elizabeth Ann
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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