Results 111 to 120 of about 3,863,870 (310)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Māori outcome evaluation: A kaupapa Māori, outcomes and indictors, framework and methodology [PDF]
, 2009 Territorial local authorities (i.e. regional and district councils) are by law required to provide for Māori values and interests, and to undertake plan evaluation and environmental monitoring, to ensure that the provisions they have in place for these ...
Jefferies, Richard, Kennedy, Nathan
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Personality Testing in the Church of Scientology: \ud Implications for Outcome Research\ud [PDF]
, 2013 Many fields of modern society require scientific proof of effectiveness before new methods can be widely accepted, as in clinical trials for new drugs, educational evaluation for teaching approaches, and outcome studies for psychological interventions ...
Wolfe, John
core
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Evaluation of patient-reported outcomes relevant for patients with benign liver tumours [PDF]
, 2021 Alicia Furumaya +9 more
openalex +1 more source
Structural Policy Challenges in Slovakia [PDF]
The paper presents possible approaches for measuring the quality of life together with their strengths and weaknesses. We identify 10 outcome indicators, which could help not only to set targets, but also as a quantitative benchmark for structural policy
Ludovit Odor +3 more
core
How Can You Measure the Productivity of Knowledge Workers? [PDF]
, 2017 [Excerpt] According to Peter Drucker (1999), the most valuable assets of a 21st century organization would be its knowledge workers and their productivity.
Shibalayeva, Sabina, Zhu, Julia
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source