Results 151 to 160 of about 8,503,104 (286)
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Subjective outcome evaluation of a gifted education program: the Project GIFT in Hong Kong. [PDF]
Shek DTL +4 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Xiaofeng Chen,1,* Xin Zhang,1,* Feifei Nie,2 Xiujun Wang,3 Jiewen Zhang,2 Xiuhua Wang,4 Chen Lv3 1Department of Intensive Care Unit, Beijing Chest Hospital, Capital Medical University, Beijing, 101149, People’s Republic of China ...
Chen X +6 more
doaj
Neurophysiological prediction of competitive orientation via EEG during outcome evaluation in gamified learning. [PDF]
Watanabe H, Tabata A, Ishii C, Naruse Y.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Investigating Patient Outcome Measures in Mental Health [PDF]
This report examines the feasibility of incorporating patient outcomes in mental health into a productivity measure. It examines which outcome measures are most commonly used in mental health, the practical issues about collecting these outcome measures,
Rowena Jacobs
core
Process and Outcome Evaluation of the National Institutes of Health Community Engagement Alliance. [PDF]
Chansky MC +9 more
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Evaluation of the World Bank Group Program
IEG’s Country Program Evaluation (CPE) covers the period FY05–13. The period spans three World Bank Group country strategies and one progress report. It also covers the last years of the Ben Ali regime and the
Independent Evaluation Group
core

