The Neglected Role of GSDMD C‐Terminal in Counteracting Type I Interferon Signaling
The C‐terminal domain of Gasdermin D (GSDMD‐CT) shows functions beyond pyroptosis. GSDMD‐CT negatively regulates IFN‐I signaling during viral infection by triggering autophagic degradation of RIG‐I and TBK1. GSDMD‐CT interacts with retinoic acid‐inducible gene‐I (RIG‐I) and tank‐binding kinase 1 (TBK1), leading to TRIM28‐mediated ubiquitination and ...
Weilv Xu+17 more
wiley +1 more source
The effect of interprofessional game-based learning on perceived cognitive load and self-efficacy in interprofessional communication and collaboration in patient safety incidents. [PDF]
Hosseinpour A, Keshmiri F.
europepmc +1 more source
Iron‐induced lipid peroxidation of phosphatidylethanolamine (PE) species is the key driver of ferroptosis. The authors discovered that PHOSPHO1 lowers the level of PE in retinal pigment epithelial cells thus reducing the formation of lipid peroxides. Lowering PE levels can also prevent the creation of autolysosomes, reduce the production of free iron ...
Zhiyang Chen+19 more
wiley +1 more source
Voice attractiveness affects cooperative behavior in the Stag Hunt Game: evidence from neural electrophysiology. [PDF]
Wang X, Cui W.
europepmc +1 more source
Bioinspired Brush Reinforced Solid Slippery Coatings for Marine Photovoltaic Protection
Plant cuticles exhibit exceptional liquid repellency and self‐healing properties, providing a novel strategy for the multifunctional self‐cleaning materials. A plant‐inspired solid slippery surface (PI‐SSS) based on surface‐grafted poly(ionic liquid) brushes and lubricating copolymer via ion‐dipole interactions are introduced, effectively protecting ...
Ling Yin+7 more
wiley +1 more source
Mind the semantic gap: semantic efficiency in human computer interfaces. [PDF]
Horsley J.
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Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia+8 more
wiley +1 more source
Promoting the modal shift of freight from road to rail in China: An evolutionary game and simulation study. [PDF]
Liu S, Jia G.
europepmc +1 more source
Data-driven mechanisms for network freight platforms: An evolutionary game perspective. [PDF]
He C, Xu Q, Xu X, Kong F, Shen F.
europepmc +1 more source