Results 141 to 150 of about 14,326,866 (362)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Patient Related Outcome Measures, 2019 Anil Gumber, Bhanu Ramaswamy, Oranuch Thongchundee Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield S10 2BP, UKCorrespondence: Anil GumberFaculty of Health and Wellbeing, Sheffield Hallam University, Collegiate Hall, Sheffield S10 ...
Gumber A, Ramaswamy B, Thongchundee O
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Patient Related Outcome Measures, 2020 Carla M Bastemeijer,1 Hileen Boosman,2 Linda Zandbelt,3 Reinier Timman,4 Dolf de Boer,5 Jan A Hazelzet1 1Department of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands; 2Department of Quality & Patient Safety, Leiden ...
Bastemeijer CM +5 more
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Identifying the concepts contained in outcome measures of clinical trials on obesity using the international classification of functioning disability and health as a reference [PDF]
, 2007 The objective of this doctoral thesis was to examine the use of concepts contained in outcome measures of randomized controlled obesity trials (RCTs) between 1992 und 2001, using the ICF as a reference ...
Baumann, Sebastian
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Patient Related Outcome Measures, 2010 Evalill Nilsson1, Margareta Kristenson21Department of Social and Welfare Studies, Linköping University, Linköping, Sweden; 2Department of Medicine and Health, Division of Community Medicine/Social Medicine and Public Health Sciences ...
Evalill Nilsson, Margareta Kristenson
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source