Results 11 to 20 of about 1,561,444 (269)
The Lancet Neurology has great pleasure in commemorating 40 years since the development of the Glasgow Coma Scale (GCS). Not only has the scale become the standard for the measurement of consciousness level, its has subsequently expanded to provide applications in risk assessment, trend monitoring, classifi cation, and prognosis.
openaire +2 more sources
In the context of health and illness, outcome is usually defined as the extent to which goals are achieved. It is necessary to understand: (i) the conceptual basis of the consequences of stroke; (ii) the context of measurement; and (iii) the calibre of the instruments available.
openaire +2 more sources
Traditional outcome measurement scales, such as the Medical Research Council (MRC) score, the Active Movement Scale (AMS), and Mallet score, are used by surgeons to assess outcomes in patients with obstetric brachial plexus palsy (OBPP). The measurement scales used to evaluate patients fall under the International Classification of Functioning (ICF ...
Gupta, Shivani +5 more
openaire +3 more sources
Outcome measures measure outcomes, not effects of intervention
Historically, measurement of clinical outcomes was not a feature of routine clinical practice. Physiotherapists (and, for that matter, most other health professionals) did not systematically collect data on patients’ outcomes. Typically physiotherapists obtained incidental impressions of clinical outcomes from clinical observations, or from patients ...
Herbert, Robert +3 more
openaire +2 more sources
AbstractIntroductionAdvances in haemophilia treatment have resulted in a near‐normal life expectancy, lower burden of bleeding and treatment, and improved quality of life in high‐income countries. Bleeding rate is approaching zero and novel parameters should be evaluated to assess the efficacy of treatment not only from the clinical point of view by ...
Giancarlo Castaman +3 more
openaire +2 more sources
ABSTRACT Background Adolescents with high‐risk cancer face complex developmental, psychosocial, and ethical challenges that extend beyond disease‐directed treatment. Although international recommendations exist for communication, psychosocial care, pediatric palliative care, survivorship, and shared decision‐making, these have largely evolved within ...
Johanna M. C. Blom +15 more
wiley +1 more source
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld +5 more
wiley +1 more source
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Christine de la Loge,1 Fatoumata Fofana,2 Paul Williams,1 Sarah Rusch,3 Marita Stevens,4 Jane Scott5 1Patient-Centered Outcomes, Mapi (an ICON Plc. company), Lyon, France; 2Patient-Centered Outcomes, Mapi (an ICON Plc.
de la Loge C +5 more
doaj
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source

