Results 131 to 140 of about 16,988,510 (382)
Summary of the Commissioning Better Outcomes Evaluation [PDF]
The aim of the evaluation is to improve the understanding of SIBs, by capturing learning at all stages of the development process and building an evidence base for the SIB model and its application in different contexts.
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Depression: An actionable outcome for those at clinical high-risk
J. Addington +15 more
openalex +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Predicting Outcomes in Investment Treaty Arbitration [PDF]
Crafting appropriate dispute settlement processes is challenging for any conflict-management system, particularly for politically sensitive international economic law disputes.
Franck, Susan D., Wylie, Lindsey E.
core +1 more source
Adverse Family Social Circumstances and Outcome in Pediatric Cardiac Transplant Recipients at a UK Center [PDF]
Kate Brown +7 more
openalex +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Meryl Brod,1 Kathryn M Pfeiffer,1 Suzanne Lessard Alolga,1 Jane F Beck,1 Morgan Murphy,2 Aleksandra K Bruchey,3 Aristides Maniatis,4 Pisit Pitukcheewanont5 1Health Outcomes Research, The Brod Group, Mill Valley, CA, USA; 2Research & Development ...
Brod M +7 more
doaj

