Results 121 to 130 of about 10,999,837 (292)
Working Together Toward Better Health Outcomes [PDF]
, 2017 Healthcare organizations and community-based organizations (CBOs) that provide human services are partnering in shared pursuit of better health outcomes.
Elise Miller, Laura Line, Trishna Nath
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Who Is Caring for the Caregiver? The Role of Cybercoping for Dementia Caregivers [PDF]
, 2018 The purpose of this study is to investigate the relationship between dementia caregivers’ communication behaviors (information seeking and forwarding) and their outcomes (coping outcomes: e.g., dealing better with negative feelings or improved medical ...
Chon, Myoung-Gi +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Patient Preference and AdherenceMeryl Brod,1 Kathryn M Pfeiffer,1 Suzanne Lessard Alolga,1 Jane F Beck,1 Morgan Murphy,2 Aleksandra K Bruchey,3 Aristides Maniatis,4 Pisit Pitukcheewanont5 1Health Outcomes Research, The Brod Group, Mill Valley, CA, USA; 2Research & Development ...
Brod M +7 more
doaj
The impact of environmental resources on the stress process : encouraging positive outcomes in the workplace : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Turitea, New Zealand [PDF]
, 2008 The present study investigated resources in the organisational environment which would increase the likelihood of positive outcomes from the stress process.
Van der Merwe, Anika
core