Results 141 to 150 of about 15,903,898 (384)

Outcomes

open access: yes, 2021
The following outcomes will be analysed:Operative timeLN harvestedBlood lossAnalgesic requirementTime to first flatusTime to oral intakeOverall morbidityMajor complications (Clavien-Dindo III-IV)Length of stayMortalityThree-year overall survivalFive-year overall ...
openaire   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Developing a Process for Preference Measures in Pediatric Growth Hormone Deficiency: Challenges and Solutions

open access: yesPatient Preference and Adherence
Meryl Brod,1 Kathryn M Pfeiffer,1 Suzanne Lessard Alolga,1 Jane F Beck,1 Morgan Murphy,2 Aleksandra K Bruchey,3 Aristides Maniatis,4 Pisit Pitukcheewanont5 1Health Outcomes Research, The Brod Group, Mill Valley, CA, USA; 2Research & Development ...
Brod M   +7 more
doaj  

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Real-world association between systemic corticosteroid exposure and complications in US patients with severe asthma

open access: yesAllergy, Asthma & Clinical Immunology
Background Systemic corticosteroid (SCS) use remains widespread among patients with severe asthma, despite associated complications. Objective Evaluate the association between cumulative SCS exposure and SCS-related complications in severe asthma ...
Thomas B Casale   +7 more
doaj   +1 more source

Poststroke Outcomes [PDF]

open access: yesStroke Research and Treatment, 2014
Bruce Ovbiagele   +3 more
openaire   +3 more sources

Outcome

open access: yes, 2019
A number of outcome measures are available to assess the impact of sports injuries of the foot and ankle. The following key items are essential when selecting the best available outcome measures: History taking remains the most important tool and is essential to assess the symptoms, concerns, medical-, social-, and psychological history and to ...
Altink, J. Nienke   +3 more
openaire   +2 more sources

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