Results 221 to 230 of about 16,988,510 (382)

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

New England Journal of Medicine, 2008
Anushka Patel, S. MacMahon, J. Chalmers, B. Neal, L. Billot, M. Woodward, M. Marre, M. Cooper, P. Glasziou, D. Grobbee, P. Hamet, S. Harrap, S. Heller, Li-sheng Liu, G. Mancia, C. Mogensen, C. Pan, N. Poulter, A. Rodgers, B. Williams, Severine Bompoint, B. D. de Galan, R. Joshi, F. Travert   +23 more
semanticscholar   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

The relationship between microbial contaminations of embryo transfer catheters with pregnancy outcome after embryo transfer

, 2023
Masomeh Rezaie, Mohammad Jafar Rezaie, Fariba Seyedoshohadaie, Azra Alahvaisi, Khalil Azizian, Bijan Nouri, Samira Babaneghad Gajoti   +6 more
openalex   +1 more source

Incidence and outcomes of acute lung injury.

New England Journal of Medicine, 2005
G. Rubenfeld, E. Caldwell, E. Peabody, J. Weaver, Diane P. Martin, M. Neff, E. Stern, L. Hudson   +7 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

GrantWatch: Outcomes [PDF]

Health Affairs, 2009
openaire   +2 more sources

The Patient-Reported Outcomes Measurement Information System (PROMIS) developed and tested its first wave of adult self-reported health outcome item banks: 2005-2008.

Journal of Clinical Epidemiology, 2010
D. Cella, William T. Riley, A. Stone, N. Rothrock, B. Reeve, S. Yount, D. Amtmann, R. Bode, Daniel J Buysse, Seung W. Choi, K. Cook, R. Devellis, D. DeWalt, J. Fries, R. Gershon, E. Hahn, J. Lai, P. Pilkonis, D. Revicki, M. Rose, K. Weinfurt, R. Hays   +21 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Staffing and leadership as drivers of nurse retention: A work environment analysis. [PDF]

Nurs Manage
Losty LS, Pascale A, Warshawsky NE.
europepmc   +1 more source