Results 61 to 70 of about 10,882,011 (287)
Health and Quality of Life Outcomes, 2023 Background Psoriasis is a common autoimmune dermatologic condition which has a pronounced negative impact on patient quality of life and disease burden.
Stacie Hudgens +4 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Psychometric properties of the FACT-M questionnaire in patients with Merkel cell carcinoma
Health and Quality of Life Outcomes, 2017 Background No validated disease-specific questionnaires exist to capture health-related quality of life (HRQoL) in patients with Merkel cell carcinoma (MCC).
Murtuza Bharmal +6 more
doaj +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Family stressors and children's outcomes [PDF]
, 2012 The research reported here aimed to identify:1.which family stress factors and parental behaviours were associated with worse outcomes for children at age 7 andwhich factors helped children to succeed2.whether stressful life events experienced at ...
Gutman, Leslie +2 more
core
Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]
, 2018 Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D +2 more
core +2 more sources
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
INFLUENCE OF INTENSITY, MOTIVATION AND INTEREST MEDIA AS A LEARNING COMPUTER USE OF STUDENT LEARNING LESSONS IN CURRENCY INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) IN JUNIOR HIGH SCHOOL (SMPN) 14 PURWOREJO [PDF]
, 2013 The research aim to find out : (1) Influence the intensity of the use of computers as a medium of learning on student learning outcomes in ICT subjects at Junior High School 14 Purworejo.
Rifka, Fauzia
core
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source