Results 121 to 130 of about 652,032 (313)

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

open access: yesAdvanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi   +7 more
wiley   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son   +12 more
wiley   +1 more source

Exploring bacterial outer membrane barrier to combat bad bugs

open access: yesInfection and Drug Resistance, 2017
Ishan Ghai,1 Shashank Ghai2 1School of Engineering and Life Sciences, Jacobs University, Bremen, 2Leibniz University, Hannover, Germany Abstract: One of the main fundamental mechanisms of antibiotic resistance in Gram-negative bacteria comprises an ...
Ghai I, Ghai S
doaj  

Lifting the lid on pilus assembly

open access: yeseLife, 2014
A combination of computer simulations, evolutionary analysis and graph theory has provided new insights into the assembly of pili on the surface of bacteria.
Han Remaut, Nir Ben-Tal
doaj   +1 more source

SChloro: directing Viridiplantae proteins to six chloroplastic sub-compartments [PDF]

open access: yes, 2016
Motivation: Chloroplasts are organelles found in plants and involved in several important cell processes. Similarly to other compartments in the cell, chloroplasts have an internal structure comprising several sub-compartments, where different proteins ...
Casadio, Rita   +3 more
core   +2 more sources

Hybrid Microdiscs for Magnetically Induced Non‐Cytotoxic Thermal Actuation and Programmable Biomolecule Delivery

open access: yesAdvanced Functional Materials, EarlyView.
Hybrid magnetic microdiscs with customizable size and composition are engineered through refined photolithography and LbL assembly. Embedded Fe3O4 nanoparticles enable localized, non‐cytotoxic heating, while protein cargos can be incorporated in tunable quantities.
Daniela Iglesias‐Rojas   +13 more
wiley   +1 more source

Allosteric signalling in the outer membrane translocation domain of PapC usher

open access: yeseLife, 2014
PapC ushers are outer-membrane proteins enabling assembly and secretion of P pili in uropathogenic E. coli. Their translocation domain is a large β-barrel occluded by a plug domain, which is displaced to allow the translocation of pilus subunits across ...
Irene Farabella   +8 more
doaj   +1 more source

Domain organization of long autotransporter signal sequences [PDF]

open access: yes, 2010
Bacterial autotransporters represent a diverse family of proteins that autonomously translocate across the inner membrane of Gram-negative bacteria via the Sec complex and across the outer bacterial membrane.
Hiß, Jan Alexander   +1 more
core   +1 more source

Nanodiamond‐Based Quantum Sensing Reveals Changes in Endo‐Lysosomal Activity of Stimulated Cardiac Fibroblasts in a Cellular Fibrosis Model

open access: yesAdvanced Functional Materials, EarlyView.
Quantum sensing reveals intricate patterns linking endo‐lysosomal maturation to cardiac fibrosis progression, highlighting complexity in cellular remodeling. This study investigates fibroblast‐to‐myofibroblast transition under cell aging, stiffness, and TGF‐β stimulation, comparing nanodiamond uptake, endo‐lysosomal dynamics, and free radical ...
Aldona Mzyk   +3 more
wiley   +1 more source

Green light for chloroplast outer-membrane proteins

open access: yesNature Cell Biology, 2008
Most chloroplast proteins are encoded in the cell nucleus, translated in the cytosol, and targeted to the organelle in a post-translational manner. Our understanding of how proteins are targeted to the outer envelope membrane of chloroplasts has been improved with the identification of a specific soluble sorting factor.
Bédard, J, Jarvis, P
openaire   +3 more sources

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