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Outer Membrane Biogenesis [PDF]
Annual Review of Microbiology, 2017 The hallmark of gram-negative bacteria and organelles such as mitochondria and chloroplasts is the presence of an outer membrane. In bacteria such as Escherichia coli, the outer membrane is a unique asymmetric lipid bilayer with lipopolysaccharide in the outer leaflet.
Thomas Šilhavý +2 more
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Breaking the outer membrane barrier: structure, targets, and antimicrobial strategies for Gram-negative bacteria [PDF]
Frontiers in MicrobiologyMultidrug resistance in Gram-negative bacteria has become a significant global public health challenge, threatening human health and clinical treatment outcomes. The unique outer membrane structure of these pathogens greatly limits antibiotic penetration,
Fanzhuo Xu +3 more
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Frontiers in Microbiology, 2022 Citrus Huanglongbing (HLB) is the most devastating citrus disease in the world. Candidatus Liberibacter asiaticus (Las) is the prevalent HLB pathogen, which is yet to be cultivated.
Yixiao Huang +5 more
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Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. [PDF]
PLoS ONE, 2011 Acinetobacter baumannii is an important nosocomial pathogen that causes a high morbidity and mortality rate in infected patients, but pathogenic mechanisms of this microorganism regarding the secretion and delivery of virulence factors to host cells have
Jong Sook Jin +6 more
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Recognition of outer membrane proteins using multiple feature fusion
Frontiers in Genetics, 2023 Introduction: Outer membrane proteins are crucial in maintaining the structural stability and permeability of the outer membrane. Outer membrane proteins exhibit several functions such as antigenicity and strong immunogenicity, which have potential ...
Wenxia Su +6 more
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Frontiers in Microbiology, 2021 Gram-negative bacteria such as Escherichia coli are surrounded by an outer membrane, which encloses a peptidoglycan layer. Even if thinner than in many Gram-positive bacteria, the peptidoglycan in E.
Taiki Chikada +5 more
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Protein Quality Control at the Mitochondrial Surface
Frontiers in Cell and Developmental Biology, 2021 Mitochondria contain two membranes, the outer and inner membrane. The outer membrane fulfills crucial functions for the communication of mitochondria with the cellular environment like exchange of lipids via organelle contact sites, the transport of ...
Fabian den Brave +2 more
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Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida [PDF]
Journal of Bacteriology, 2012 Francisella spp. are highly infectious and virulent bacteria that cause the zoonotic disease tularemia. Knowledge is lacking for the virulence factors expressed by Francisella and how these factors are secreted and delivered to host cells. Gram-negative bacteria constitutively release outer membrane vesicles (OMV), which may function in the delivery of
William D, McCaig +2 more
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A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance
Applied Sciences, 2023 Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
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The Leptospiral Outer Membrane [PDF]
, 2014 The outer membrane (OM) is the front line of leptospiral interactions with their environment and the mammalian host. Unlike most invasive spirochetes, pathogenic leptospires must be able to survive in both free-living and host-adapted states. As organisms move from one set of environmental conditions to another, the OM must cope with a series of ...
David A, Haake, Wolfram R, Zückert
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