Results 11 to 20 of about 484,998 (266)

The Mitochondrial Import Complex MIM Functions as Main Translocase for α-Helical Outer Membrane Proteins

open access: yesCell Reports, 2020
Summary: The mitochondrial outer membrane contains integral proteins with α-helical membrane anchors or a transmembrane β-barrel. The translocase of the outer membrane (TOM) cooperates with the sorting and assembly machinery (SAM) in the import of β ...
Kim Nguyen Doan   +9 more
doaj   +1 more source

Genetic and Chemical-Genetic Interactions Map Biogenesis and Permeability Determinants of the Outer Membrane of Escherichia coli

open access: yesmBio, 2020
Gram-negative bacteria are intrinsically resistant to many antibiotics due to their outer membrane barrier. Although the outer membrane has been studied for decades, there is much to uncover about the biology and permeability of this complex structure ...
Kristina Klobucar   +4 more
doaj   +1 more source

Outer membrane vesicle vaccines [PDF]

open access: yesSeminars in Immunology, 2020
Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. Following the success of the MeNZB OMV vaccine in controlling an outbreak of N.
Francesca, Micoli, Calman A, MacLennan
openaire   +2 more sources

Surface Antigens of the Syphilis Spirochete and Their Potential as Virulence Determinants

open access: yesEmerging Infectious Diseases, 1997
A unique physical feature of Treponema pallidum, the venereally transmitted agent of human syphilis, is that its outer membrane contains 100-fold less membrane-spanning protein than the outer membranes of typical gram-negative bacteria, a property that ...
David R. Blanco   +2 more
doaj   +1 more source

Proteomic Analysis of Outer Membrane Proteins from Salmonella Enteritidis Strains with Different Sensitivity to Human Serum. [PDF]

open access: yesPLoS ONE, 2016
Differential analysis of outer membrane composition of S. Enteritidis strains, resistant to 50% normal human serum (NHS) was performed in order to find factors influencing the resistance to higher concentrations of NHS. Ten S.
Bartłomiej Dudek   +7 more
doaj   +1 more source

The Ton Motor

open access: yesFrontiers in Microbiology, 2022
The Ton complex is a molecular motor at the inner membrane of Gram-negative bacteria that uses a proton gradient to apply forces on outer membrane (OM) proteins to permit active transport of nutrients into the periplasmic space.
Anna C. Ratliff   +2 more
doaj   +1 more source

Bacterial outer membrane vesicle-based cancer nanovaccines

open access: yesCancer Biology & Medicine, 2022
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune recognition and killing of tumor cells.
Xiaoyu Gao   +3 more
doaj   +1 more source

Emerging Roles for NlpE as a Sensor for Lipoprotein Maturation and Transport to the Outer Membrane in Escherichia coli

open access: yesmBio, 2019
Outer membrane biogenesis is a complex process for Gram-negative bacteria as the components are synthesized in the cytoplasm or at the inner membrane and then transported to the outer membrane.
Brent W. Simpson, M. Stephen Trent
doaj   +1 more source

The Treponema pallidum Outer Membrane [PDF]

open access: yes, 2017
The outer membrane (OM) of Treponema pallidum, the uncultivatable agent of venereal syphilis, has long been the subject of misconceptions and controversy. Decades ago, researchers postulated that T. pallidum's poor surface antigenicity is the basis for its ability to cause persistent infection, but they mistakenly attributed this enigmatic property to ...
Justin D, Radolf, Sanjiv, Kumar
openaire   +2 more sources

Analysis of Moraxella catarrhalis Outer Membrane Protein Profiles

open access: yesBio-Protocol, 2013
Phenotypes observed for certain Moraxella catarrhalis wild-type strains or mutants may be caused by a variety of factors including alteration of outer membrane protein composition. Examination of the outer membrane protein profiles may be a valuable tool
Stefan de Vries, Hester Bootsma
doaj   +1 more source

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