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A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

open access: yesApplied Sciences, 2023
Gram-negative bacteria can resist antibiotics by changing the permeability via their outer membrane. These bacteria have a complex cell envelope that incorporates an outer membrane separating the periplasm from the external environment.
Ishan Ghai
doaj   +1 more source

Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida [PDF]

open access: yesJournal of Bacteriology, 2012
Francisella spp. are highly infectious and virulent bacteria that cause the zoonotic disease tularemia. Knowledge is lacking for the virulence factors expressed by Francisella and how these factors are secreted and delivered to host cells. Gram-negative bacteria constitutively release outer membrane vesicles (OMV), which may function in the delivery of
William D, McCaig   +2 more
openaire   +2 more sources

Protein Quality Control at the Mitochondrial Surface

open access: yesFrontiers in Cell and Developmental Biology, 2021
Mitochondria contain two membranes, the outer and inner membrane. The outer membrane fulfills crucial functions for the communication of mitochondria with the cellular environment like exchange of lipids via organelle contact sites, the transport of ...
Fabian den Brave   +2 more
doaj   +1 more source

The Leptospiral Outer Membrane [PDF]

open access: yes, 2014
The outer membrane (OM) is the front line of leptospiral interactions with their environment and the mammalian host. Unlike most invasive spirochetes, pathogenic leptospires must be able to survive in both free-living and host-adapted states. As organisms move from one set of environmental conditions to another, the OM must cope with a series of ...
David A, Haake, Wolfram R, Zückert
openaire   +2 more sources

Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection

open access: yesJournal of Biomedical Sciences, 2020
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing serious nosocomial infections, which is considered as the most threatening Gram-negative bacteria (GNB).
D. Nie   +7 more
semanticscholar   +1 more source

The Mitochondrial Import Complex MIM Functions as Main Translocase for α-Helical Outer Membrane Proteins

open access: yesCell Reports, 2020
Summary: The mitochondrial outer membrane contains integral proteins with α-helical membrane anchors or a transmembrane β-barrel. The translocase of the outer membrane (TOM) cooperates with the sorting and assembly machinery (SAM) in the import of β ...
Kim Nguyen Doan   +9 more
doaj   +1 more source

Genetic and Chemical-Genetic Interactions Map Biogenesis and Permeability Determinants of the Outer Membrane of Escherichia coli

open access: yesmBio, 2020
Gram-negative bacteria are intrinsically resistant to many antibiotics due to their outer membrane barrier. Although the outer membrane has been studied for decades, there is much to uncover about the biology and permeability of this complex structure ...
Kristina Klobucar   +4 more
doaj   +1 more source

Proteomic Analysis of Outer Membrane Proteins from Salmonella Enteritidis Strains with Different Sensitivity to Human Serum. [PDF]

open access: yesPLoS ONE, 2016
Differential analysis of outer membrane composition of S. Enteritidis strains, resistant to 50% normal human serum (NHS) was performed in order to find factors influencing the resistance to higher concentrations of NHS. Ten S.
Bartłomiej Dudek   +7 more
doaj   +1 more source

Outer membrane permeability and antibiotic resistance

open access: yesBiochimica Et Biophysica Acta - Proteins and Proteomics, 2009
Anne H Delcour
exaly   +2 more sources

Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]

open access: yes, 2007
Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Philippar, Katrin   +2 more
core   +1 more source

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