Results 211 to 220 of about 163,240 (292)

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Identification of Outer Membrane Vesicles as a New Vehicle Mediating Antibiotic Resistance Gene Transfer in Campylobacter. [PDF]

J Extracell Vesicles
Zhao M, He M, Lin X, Wu K, Yang F, Chen X, Li H, Wang H, Tang Y.   +8 more
europepmc   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Porphyromonas gingivalis-derived outer membrane vesicles travel from oral to distant organs via blood circulation in a time-dependent manner. [PDF]

BMC Oral Health
Lv C, Shi K, Guo Z, Luo P, Wu Z, Yu P.
europepmc   +1 more source

Interaction Between Actin and Microtubules During Plant Development

Cytoskeleton, EarlyView.
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu, Lidong Gao, M. Arif Ashraf, Qiong Nan   +3 more
wiley   +1 more source

FomA-Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL-6-Dependent M2b Macrophage Polarization. [PDF]

Adv Sci (Weinh)
Shangguan W, Li W, Huang W, Wu J, Yu Y, Huang Y, Yang L, Xie M, Yang Q, Zheng J, Zhu Y, Sun Q, Li B, Li L, Wang Z, Zhao J, Wu P, Cheng B.   +17 more
europepmc   +1 more source

Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Inhalable engineered probiotic outer membrane vesicles co-expressing multiple mpox antigens induce potent specific systemic and mucosal immune responses. [PDF]

Mater Today Bio
Fu X, Wang W, Duan H, Gao L, Wei Z, Wu Y, Wang J, Ma F, Zhang Y, Jia Y, Gu Q, He C, Wang Y, Liu X, Jiang D, Liu Z, Liao W, Ma X, Wang S, Lu Y, Shen C, Li B, Liao Y, Ma W.   +23 more
europepmc   +1 more source

Possible role of microtubules in vesicular transport of matrix protein during sea urchin larval biomineralization

Developmental Dynamics, EarlyView.
Abstract Background Biomineralization is a vital biological process through which organisms produce mineralized structures such as shells, skeletons, and teeth. Microtubules are essential for biomineralization in various eukaryotic species; however, their specific roles in this process remain unclear.
Areen Qassem, Tsvia Gildor, Smadar Ben‐Tabou de‐Leon   +2 more
wiley   +1 more source

Investigating the activation of the immune response by outer membrane vesicles from Bacteroides fragilis using a human gastrointestinal cell system. [PDF]

J Immunol
Jefferis TM, Scano C, Ashraf A, Stevens DM, Sevcik A, Bruce E, Greathouse L, Sayes CM.   +7 more
europepmc   +1 more source