Results 221 to 230 of about 1,694,595 (291)

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Cytokine-bearing Bacterial Outer Membrane Vesicles with Empowered Efficacy in Intratumoral Immunotherapy

Corbellari R, Tomasi M, Benedet M, Gagliardi A, Begaj R, Zanella I, Tamburini S, Caproni E, Shaba E, Di Lascio G, Facchini V, Baraldi C, Gambini G, Berti A, Lunardi A, Bini L, Grandi G, Grandi A.   +17 more
europepmc   +1 more source

Corrigendum to "Fusobacterium nucleatum outer membrane vesicles activate autophagy to promote oral cancer metastasis" [J. Adv. Res. 56 (2024) 167-179]. [PDF]

J Adv Res
Chen G, Gao C, Jiang S, Cai Q, Li R, Sun Q, Xiao C, Xu Y, Wu B, Zhou H.   +9 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Escherichia coli Nissle 1917 alleviates Alzheimer's disease in mice through OmpA-containing outer membrane vesicles. [PDF]

Cell Rep Med
Xie J, Dai XJ, Li Q, Zhang W, Nie X, Ji H, Chen X, Wang Y, Feng J, Li Z, Liu Q, Ye J, Zhang G, Nie S.   +13 more
europepmc   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Comparative Proteomic Profiling of Clinical <i>Klebsiella pneumoniae</i> Strains and the Corresponding Outer Membrane Vesicles. [PDF]

J Extracell Biol
Li Z, Xi J, Jia X, He Y, Wang G, Chen S, Chu X, Zhang Q, Zhu Y, Yu W, Jia P, Liu X, Yang Q.   +12 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

<i>Vibrio vulnificus</i> outer membrane vesicles induce mitochondrial dysfunction in macrophages via the TNF signaling pathway. [PDF]

Front Vet Sci
Li J, Wang L, Zhou Y, Fan L, Lou Y, Xiao X, Gao S.   +6 more
europepmc   +1 more source

Harnessing bacterial extracellular vesicles for bone and cartilage organoids

BMEMat, EarlyView.
This review presents bacterial extracellular vesicles (BEVs) as programmable bioactive regulators for bone and cartilage organoids by delivering functional cargos that modulate skeletal remodeling. It highlights key engineering strategies and future directions to advance next‐generation organoid models for bone aging related diseases.
Han Liu, Xukun Lv, Ting Cheng, Lei Yan, Yuxiao Lai, Keying Guo, Yingying Jing, Hao Shen, Jiacan Su   +8 more
wiley   +1 more source