Results 261 to 270 of about 91,336 (295)

Immune modulation by bacterial outer membrane vesicles

Nature Reviews Immunology, 2015
Gram-negative bacteria shed extracellular outer membrane vesicles (OMVs) during their normal growth both in vitro and in vivo. OMVs are spherical, bilayered membrane nanostructures that contain many components found within the parent bacterium. Until recently, OMVs were dismissed as a by-product of bacterial growth; however, findings within the past ...
Maria, Kaparakis-Liaskos, Richard L, Ferrero   +1 more
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Biogenesis of Outer Membrane Vesicles

2012
The different steps involved in the formation and release of outer membrane vesicles (OMVs) from the parent bacteria as revealed by the experimental evidence and derived models presented by different investigators are discussed. An attempt has been made to develop a unified concept of the biogenesis of OMVs released by different Gram-negative bacteria.
S. N. Chatterjee, Keya Chaudhuri
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Acinetobacter baumannii outer membrane protein a modulates the biogenesis of outer membrane vesicles

The Journal of Microbiology, 2012
Acinetobacter baumannii secretes outer membrane vesicles (OMVs) during both in vitro and in vivo growth, but the biogenesis mechanism by which A. baumannii produces OMVs remains undefined. Outer membrane protein A of A. baumannii (AbOmpA) is a major protein in the outer membrane and the C-terminus of AbOmpA interacts with diaminopimelate of ...
Dong Chan, Moon, Chul Hee, Choi, Jung Hwa, Lee, Chi-Won, Choi, Hye-Yeon, Kim, Jeong Soon, Park, Seung Il, Kim, Je Chul, Lee   +7 more
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The “hole” story of predatory outer-membrane vesicles

Canadian Journal of Microbiology, 2018
All Gram-negative bacteria release membrane vesicles. These vesicles contain a cargo of proteins and enzymes that include one or more autolysins. Autolysins are a group of enzymes with specificity for the different linkages within peptidoglycan sacculi that if uncontrolled cause bacteriolysis.
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Role of outer membrane vesicles of bacteria

Resonance, 2015
Outer membrane vesicles are nano-sized spheres produced predominantly by gram-negative bacteria. They play a significant role in cell-to-cell communication, virulence, nutrition and protection of the bacterial cells from various stress factors. Recent evidences also underscore their involvement in antibiotic-resistance of bacteria.
M. V. Jagannadham, M. K. Chattopadhyay
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Purification of Borrelia burgdorferi Outer Membrane Vesicles

Bacterial outer membrane vesicles (OMVs) are spherical membrane constructs shed by gram-negative bacteria. OMVs produced by the Lyme disease pathogen Borrelia burgdorferi have been identified to contain such virulence factors as OspA, OspB, OspC, and genetic material.
Hanna, Tammisto, Kati, Karvonen
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Exploring the proteome of meningococcal outer membrane vesicle vaccines

PROTEOMICS – Clinical Applications, 2007
AbstractNeisseria meningitidis, one of the principal causes of bacterial meningitis and septicemia, continues to present a challenge for vaccine developers. While significant progress has been made in the development and implementation of conjugate vaccines, which are based on the capsular polysaccharide of the organism, this approach has failed to ...
Jun X, Wheeler, Caroline, Vipond, Ian M, Feavers   +2 more
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Outer Membrane Vesicles as Carriers of Biomaterials

2012
During their formation the outer membrane vesicles (OMVs) entrap, utilizing some special sorting mechanism, different materials from the periplasm and/or the outer membrane of the bacterial cell for purposes favoring the parent bacteria and against the survival of other competing organisms either in vitro or in vivo.
S. N. Chatterjee, Keya Chaudhuri
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Outer Membrane Vesicles and the Biofilm Formation

2012
Plenty of outer membrane vesicles (OMVs) are often found associated with the parent bacteria forming a biofilm. The functions of these OMVs in the biofilm are discussed in this chapter. Additional genetic and other studies are required to decide the exact role of OMVs and DNA in the formation of biofilm.
S. N. Chatterjee, Keya Chaudhuri
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Glycoengineered Outer Membrane Vesicles as a Platform for Vaccine Development

2017
As we enter into the postantibiotic era, vaccines to prevent bacterial infections previously treatable with antibiotics are urgently needed. Most successful antibacterial vaccines are glycoconjugates, composed of cell surface carbohydrates chemically attached to a carrier protein.
Ezequiel, Valguarnera, Mario F, Feldman
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