Results 41 to 50 of about 91,336 (295)

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

Nature Communications, 2016
Bacteria release outer membrane vesicles (OMVs) that play important roles in pathogenesis and intercellular interactions. Here, Roier et al. provide evidence supporting that phospholipid accumulation in the outer leaflet of the outer membrane ...
Sandro Roier, Franz G. Zingl, Fatih Cakar, Sanel Durakovic, Paul Kohl, Thomas O. Eichmann, Lisa Klug, Bernhard Gadermaier, Katharina Weinzerl, Ruth Prassl, Achim Lass, Günther Daum, Joachim Reidl, Mario F. Feldman, Stefan Schild   +14 more
doaj   +1 more source

Regulation of outer-membrane proteins (OMPs) A and F, during hlyF-induced outer-membrane vesicle (OMV) biosynthesis

Heliyon, 2019
Background: Gram-negative bacteria actively secrete outer membrane vesicles into the surrounding environment and these vesicles have been shown to play various physiological and protective roles such as carrying antibiotic-degrading enzymes and acting as
Wouter André van der Westhuizen, Chrispian William Theron, Charlotte Enastacia Boucher, Robert Richard Bragg   +3 more
doaj   +1 more source

Inhibitors of Bacterial Extracellular Vesicles

Frontiers in Microbiology, 2022
Both Gram-positive and Gram-negative bacteria can secrete extracellular vesicles (EVs), which contain numerous active substances. EVs mediate bacterial interactions with their hosts or other microbes.
Jianwei Chen, Jianwei Chen, Hongfang Zhang, Siqi Wang, Yujie Du, Bin Wei, Qiang Wu, Hong Wang, Hong Wang   +8 more
doaj   +1 more source

Delivery of virulence factors by bacterial membrane vesicles to mammalian host cells

, 2020
Bacterial membrane vesicles represent a universal secretion mechanism enabling both Gram-negative and Gram-positive organisms to transfer cargo to eukaryotic cells, as well as to other bacterial cells.
Nadeem, Aftab,, Wai, Sun Nyunt,, Oscarsson, Jan,   +2 more
core   +1 more source

Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles

Frontiers in Immunology, 2021
Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth.
Shannon M. Collins, Angela C. Brown
doaj   +1 more source

The lethal cargo of Myxococcus xanthus outer membrane vesicles [PDF]

Frontiers in Microbiology, 2014
Myxococcus xanthus is a bacterial micro-predator known for hunting other microbes in a wolf pack-like manner. Outer membrane vesicles (OMVs) are produced in large quantities by M. xanthus and have a highly organized structure in the extracellular milieu, sometimes occurring in chains that link neighboring cells within a biofilm.
James E Berleman, James E Berleman, James E Berleman, Simon eAllen, Megan eDanielewicz, Jonathan P Remis, Amita eGorur, John eCunha, Masood Z Hadi, David R Zusman, H. Ewa Witkowska, Trent Russell Northen, Manfred eAuer   +12 more
openaire   +6 more sources

The invariant phenylalanine of precursor proteins discloses the importance of Omp85 for protein translocation into cyanelles [PDF]

, 2007
Background Today it is widely accepted that plastids are of cyanobacterial origin. During their evolutionary integration into the metabolic and regulatory networks of the host cell the engulfed cyanobacteria lost their independency.
Schleiff Enrico, Roman Martin, Martin, Roman, Schleiff, Enrico (Ludwig-Maximilians-Universität München (LMU)), Steiner Jürgen M, Steiner, Jürgen M., Loeffelhardt, Wolfgang, Wunder, Tobias (Ludwig-Maximilians-Universität München (LMU)), Löffelhardt Wolfgang, Steiner, Juergen M., Wunder Tobias, Martin, Roman (Ludwig-Maximilians-Universität München (LMU)), Tobias Wunder, Enrico Schleiff, Jürgen M Steiner, Martin Roman, Wunder, Tobias, Löffelhardt, Wolfgang (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Schleiff, Enrico, Löffelhardt, Wolfgang, Steiner, Juergen-Michael (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Wolfgang Löffelhardt   +21 more
core   +1 more source

Bioengineering Outer-Membrane Vesicles for Vaccine Development: Strategies, Advances, and Perspectives. [PDF]

Vaccines (Basel)
Outer-membrane vesicles (OMVs), naturally secreted by Gram-negative bacteria, have gained recognition as a versatile platform for the development of next-generation vaccines.
Zahid A, Ismail H, Wilson JC, Grice ID.
europepmc   +2 more sources

Incorporation of Plasmid DNA Into Bacterial Membrane Vesicles by Peptidoglycan Defects in Escherichia coli

Frontiers in Microbiology, 2021
Membrane vesicles (MVs) are released by various prokaryotes and play a role in the delivery of various cell-cell interaction factors. Recent studies have determined that these vesicles are capable of functioning as mediators of horizontal gene transfer ...
Sharmin Aktar, Yuhi Okamoto, So Ueno, Yuhei O. Tahara, Yuhei O. Tahara, Masayoshi Imaizumi, Masaki Shintani, Masaki Shintani, Masaki Shintani, Masaki Shintani, Makoto Miyata, Makoto Miyata, Hiroyuki Futamata, Hiroyuki Futamata, Hiroyuki Futamata, Hiroyuki Futamata, Hideaki Nojiri, Yosuke Tashiro, Yosuke Tashiro, Yosuke Tashiro, Yosuke Tashiro   +20 more
doaj   +1 more source

Bacterial outer membrane vesicle nanorobot

Proceedings of the National Academy of Sciences
Autonomous nanorobots represent an advanced tool for precision therapy to improve therapeutic efficacy. However, current nanorobotic designs primarily rely on inorganic materials with compromised biocompatibility and limited biological functions. Here, we introduce enzyme-powered bacterial outer membrane vesicle (OMV) nanorobots. The immobilized urease
Songsong Tang, Daitian Tang, Houhong Zhou, Yangyang Li, Dewang Zhou, Xiqi Peng, Chunyu Ren, Yilin Su, Shaohua Zhang, Haoxiang Zheng, Fangchen Wan, Jounghyun Yoo, Hong Han, Xiaotian Ma, Wei Gao, Song Wu   +15 more
openaire   +3 more sources