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Outer membrane vesicle vaccines for Neisseria gonorrhoeae [PDF]
Multidrug-resistant Neisseria gonorrhoeae is a global health problem, and the development of a vaccine is considered essential for the effective control of gonorrhoea. The use of outer membrane vesicle vaccines to prevent N. gonorrhoeae infection has garnered considerable interest, and a recent study using a mouse model of experimental gonococcal ...
Evgeny A. Semchenko, Kate L. Seib
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Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida [PDF]
Francisella spp. are highly infectious and virulent bacteria that cause the zoonotic disease tularemia. Knowledge is lacking for the virulence factors expressed by Francisella and how these factors are secreted and delivered to host cells. Gram-negative bacteria constitutively release outer membrane vesicles (OMV), which may function in the delivery of
William D, McCaig +2 more
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Opportunities for engineering Outer Membrane Vesicles (OMVs) using synthetic biology approaches [PDF]
Gram-negative bacteria naturally shed lipid vesicles, which contain complex molecular cargoes, from their outer membrane. These outer membrane vesicles (OMVs) have important biological functions relating to microbial stress responses, microbiome ...
Freemont, Paul +2 more
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Almost all bacteria secrete spherical membranous nanoparticles, also referred to as membrane vesicles (MVs). A variety of MV types exist, ranging from 20 to 400 nm in diameter, each with their own formation routes.
Jolien Vitse, Bart Devreese
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Outer Membrane Vesicle-Host Cell Interactions [PDF]
ABSTRACT Outer membrane vesicles (OMVs) are nanosized proteoliposomes derived from the outer membrane of Gram-negative bacteria. They are ubiquitously produced both in culture and during infection and are now recognized to play crucial roles during host-microbe interactions.
Jessica D, Cecil +3 more
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Outer-inner membrane vesicles naturally secreted by gram-negative pathogenic bacteria. [PDF]
Outer-inner membrane vesicles (O-IMVs) were recently described as a new type of membrane vesicle secreted by the Antarctic bacterium Shewanella vesiculosa M7T.
Carla Pérez-Cruz +3 more
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Microbial biosynthesis of designer outer membrane vesicles [PDF]
Outer membrane vesicles (OMVs) are nanoscale proteoliposomes that are ubiquitously secreted by Gram-negative bacteria. Interest in these bioparticles has escalated over the years, leading to discoveries regarding their composition, production, and vaccine potential.
Jenny L, Baker +4 more
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Helicobacter pylori Membrane Vesicles Stimulate Innate Pro- and Anti-Inflammatory Responses and Induce Apoptosis in Jurkat T Cells [PDF]
Persistent Helicobacter pylori infection induces chronic inflammation in the human gastric mucosa, which is associated with development of peptic ulceration, gastric atrophy, and gastric adenocarcinoma.
Winter, J +9 more
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Summary: Lipid vesicles, which mimic cell membranes in structure and components, have been used to study the origin of life and artificial cell construction.
Masato Suzuki, Koki Kamiya
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Outer membrane vesicle-based intranasal vaccines
Delivery of vaccines via the mucosal route is regarded as the most effective mode of immunization to counteract infectious diseases that enter via mucosal tissues, including oral, nasal, pulmonary, intestinal, and urogenital surfaces. Mucosal vaccines not only induce local immune effector elements, such as secretory Immunoglobulin A (IgA) reaching the ...
Peter Van der Ley, Virgil EJC Schijns
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