Results 11 to 20 of about 1,694,595 (291)
BACTERIAL OUTER MEMBRANE VESICLES AND VACCINE APPLICATIONS [PDF]
Frontiers in Immunology, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of self ...
Reinaldo eAcevedo +10 more
doaj +11 more sources
Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles. [PDF]
PLoS ONE, 2015 Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins ...
Thomas Kieselbach +3 more
doaj +5 more sources
Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium
BMC Microbiology, 2008 Background Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as virulence associated proteins, e ...
Niehaus Karsten +3 more
doaj +2 more sources
Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum [PDF]
International Journal of Dentistry, 2013 Porphyromonas gingivalis sheds outer membrane vesicles that contain several virulence factors, including adhesins. In this study, we investigated the ability of P.
Daniel Grenier
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Outer Membrane Vesicle Vaccine Platforms
BioDrugs, 2023 Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence factor for bacteria, helping them to survive through harsh environmental conditions. Native OMVs, naturally-released from bacteria, are produced at a level too low for vaccine manufacturing, requiring ...
Micoli, Francesca +2 more
openaire +2 more sources
Human Vaccines & Immunotherapeutics, 2012 Nowadays adjuvants are extensively used as immuno-stimulatory and immuno-modulatory compounds as components of subunit and combination vaccine formulations. The adjuvants of microbial origin are more frequently used among currently used licensed or experimental adjuvants.
Arfa, Moshiri +3 more
openaire +2 more sources
Opportunities for engineering Outer Membrane Vesicles (OMVs) using synthetic biology approaches [PDF]
, 2023 Gram-negative bacteria naturally shed lipid vesicles, which contain complex molecular cargoes, from their outer membrane. These outer membrane vesicles (OMVs) have important biological functions relating to microbial stress responses, microbiome ...
Freemont, Paul +2 more
core +1 more source
Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]
, 1993 Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert +5 more
core +2 more sources
Production of Outer Membrane Vesicles and Outer Membrane Tubes by Francisella novicida [PDF]
Journal of Bacteriology, 2012 Francisella spp. are highly infectious and virulent bacteria that cause the zoonotic disease tularemia. Knowledge is lacking for the virulence factors expressed by Francisella and how these factors are secreted and delivered to host cells. Gram-negative bacteria constitutively release outer membrane vesicles (OMV), which may function in the delivery of
William D, McCaig +2 more
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Outer membrane vesicle vaccines for Neisseria gonorrhoeae [PDF]
Nature Reviews Urology, 2021 Multidrug-resistant Neisseria gonorrhoeae is a global health problem, and the development of a vaccine is considered essential for the effective control of gonorrhoea. The use of outer membrane vesicle vaccines to prevent N. gonorrhoeae infection has garnered considerable interest, and a recent study using a mouse model of experimental gonococcal ...
Evgeny A. Semchenko, Kate L. Seib
openaire +3 more sources