Results 71 to 80 of about 163,240 (292)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Outer Membrane Vesicles Released From Aeromonas Strains Are Involved in the Biofilm Formation

open access: yesFrontiers in Microbiology, 2021
Aeromonas spp. are Gram-negative rod-shaped bacteria ubiquitously distributed in diverse water sources. Several Aeromonas spp. are known as human and fish pathogens.
Soshi Seike   +5 more
doaj   +1 more source

GMMA from genetically-engineered meningococcus as vaccine for Africa [PDF]

open access: yes, 2015
Gram-negative bacteria naturally shed outer membrane vesicles (OMVs). Structural changes in bacterial outer membrane lead to GMMA, Generalized Modules for Membrane Antigens: outer membrane vesicles to use as vaccine. They are safe, cheap to produce, and
Marini, Arianna
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium Xanthomonas campestris pv. campestris

open access: yesBMC Microbiology, 2008
Background Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as virulence associated proteins, e ...
Niehaus Karsten   +3 more
doaj   +1 more source

Outer membrane vesicles from bacteria: Role and potential value in the pathogenesis of chronic respiratory diseases

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Infectious diseases are the leading cause of death in both adults and children, with respiratory infections being the leading cause of death. A growing body of evidence suggests that bacterially released extracellular membrane vesicles play an important ...
Fei Han   +6 more
doaj   +1 more source

Spontaneous Expulsion of Giant Lipid Vesicles Induced by Laser Tweezers [PDF]

open access: yes, 1996
Irradiation of a giant unilamellar lipid bilayer vesicle with a focused laser spot leads to a tense pressurized state which persists indefinitely after laser shutoff.
Bar-Ziv, Roy   +3 more
core   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Release of Outer Membrane Vesicles from Bordetella pertussis

open access: yesCurrent Microbiology, 1999
The aim of the study reported here was to investigate the production of Bordetella pertussis outer membrane vesicles (OMVs). Numerous vesicles released from cells grown in Stainer-Scholte liquid medium were observed. The formation of similar vesicle-like structures could also be artificially induced by sonication of concentrated bacterial suspensions ...
Hozbor, Daniela Flavia   +5 more
openaire   +3 more sources

Packaging of Macroscopic Material Payloads: Needs, Challenges, Concepts, and Future Directions

open access: yesAdvanced Engineering Materials, EarlyView.
This review introduces a unified framework that decomposes any macroscopic packaging system into the payload, packaging material, and packaging strategy and combines them into a conceptual packaging equation: packaging strategy = payload + packaging material.
Venkata S. R. Jampani, Manos Anyfantakis
wiley   +1 more source

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