Results 31 to 40 of about 1,363,759 (285)

M-Theory Moduli Space and Cosmology [PDF]

open access: yes, 2002
We conduct a systematic search for a viable string/M-theory cosmology, focusing on cosmologies that include an era of slow-roll inflation, after which the moduli are stabilized and the Universe is in a state with an acceptably small cosmological constant.
A. Sen   +42 more
core   +2 more sources

A compactification of outer space which is an absolute retract [PDF]

open access: yes, 2018
We define a new compactification of outer space $CV_N$ (the \emph{Pacman compactification}) which is an absolute retract, for which the boundary is a $Z$-set. The classical compactification $\overline{CV_N}$ made of very small $F_N$-actions on $\mathbb{R}
Bestvina, Mladen, Horbez, Camille
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

First Detection of X-Ray Polarization in Galactic Ultraluminous X-Ray Pulsar Swift J0243.6+6124 with IXPE

open access: yesThe Astrophysical Journal Letters
We report the results of first ever spectropolarimetric analyses of the Galactic ultraluminous X-ray pulsar Swift J0243.6+6124 during the 2023 outburst using quasi-simultaneous IXPE, NICER, and NuSTAR observations.
Seshadri Majumder   +4 more
doaj   +1 more source

On Extended d-D Kappa Distribution

open access: yesAxioms
The thermal Doppler broadening of spectral profiles for particle populations in the absence or presence of potential fields can be described by kappa distributions.
Arak M. Mathai, Hans J. Haubold
doaj   +1 more source

Neutrino masses from outer space

open access: yesPhysics Letters B, 2019
Neutrinos can gain mass from coupling to an ultralight field in slow roll. When such a field is displaced from its minimum, its vev acts just like the Higgs vev in spontaneous symmetry breaking.
Guido D'Amico   +2 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Outer Space and Private Companies

open access: yesPoliteja, 2017
The paper focuses on sectors, methods, and spheres of the space activity of private companies, to provide empirical analysis of space applications and implications for global security.
Paweł Frankowski
doaj   +1 more source

The Development of Space Law: Applying the Principles of Space Law and Interpreting 'Peaceful Purposes' in the Outer Space Treaty 1967

open access: yesVolksgeist, 2021
This study analyzes the relevance of the proportionality, non-intervention, and unnecessary suffering principle's in the outer space perspective; and analyzes the 'peaceful purposes' at Outer Space Treaty 1967.
Fradhana Putra Disantara
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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