Results 51 to 60 of about 301,015 (306)

On Extended d-D Kappa Distribution

open access: yesAxioms
The thermal Doppler broadening of spectral profiles for particle populations in the absence or presence of potential fields can be described by kappa distributions.
Arak M. Mathai, Hans J. Haubold
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The Development of Space Law: Applying the Principles of Space Law and Interpreting 'Peaceful Purposes' in the Outer Space Treaty 1967

open access: yesVolksgeist, 2021
This study analyzes the relevance of the proportionality, non-intervention, and unnecessary suffering principle's in the outer space perspective; and analyzes the 'peaceful purposes' at Outer Space Treaty 1967.
Fradhana Putra Disantara
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

After Shock [PDF]

open access: yes, 2017
This catalogue essay was written to accompanyJaala Alex's 2017 exhibition at Outer Space, Brisbane, 'After Shock'. It uses the conversation format as a way to expand on the subjective content of the work in the exhibition as well as in Jaala's practice ...
Coombs, Courtney
core  

Outer Space as a Sociological Frontier [PDF]

open access: yesСоциологический журнал, 2018
The article is dedicated to the signifcance and prospects of developing a newresearch feld — astrosociology. Space studies have traditionally been the prerogative of science and technology, whereas social and cultural aspects of space exploration have ...
Evgeniya G. Nim
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The laws of war in outer space [PDF]

open access: yes, 2019
With the development of technology accelerating at a rapid pace, there has not been a more crucial time to analyze the international legal framework of outer space.
Freeland, Steven (R13494)   +1 more
core   +1 more source

Principle of the peaceful use of outer space [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2015
Principle of the peace full uses of outer space is one of the basic principle of international law. It is currently the only legal obstacle for placement and use of the weapons in outer space.
Vlajnić Jelena M.
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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