Results 61 to 70 of about 4,641,331 (294)
The sky's the limit? Establishing a legal delimitation of airspace and outer space [PDF]
, 2008 The debate over the legal delimitation between air and space has been argued for over half a century. In representing the positions of those concerned one can show the need for a boundary between airspace and outer space.
Monahan, Rhys
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Pathway to Fractional Integrals, Fractional Differential Equations, and Role of the H-Function
AxiomsIn this paper, the pathway model for the real scalar variable case is re-explored and its connections to fractional integrals, solutions of fractional differential equations, Tsallis statistics and superstatistics in statistical mechanics, the reaction ...
Arak M. Mathai, Hans J. Haubold
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Outer Space as a Global Commons: An Empirical Study of Space Arrangements
International Journal of the Commons, 2023 The designation of outer space as a global commons is a contentious issue. Some argue that officially recognizing it as such could discourage private investment, while others claim that it would not sufficiently promote sustainability.
Pauline Pic +2 more
doaj +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Fox’s H-Functions: A Gentle Introduction to Astrophysical Thermonuclear Functions
AxiomsNeeded for cosmological and stellar nucleosynthesis, we are studying the closed-form analytic evaluation of thermonuclear reaction rates. In this context, we undertake a comprehensive analysis of three largely distinct velocity distributions, namely the ...
Hans J. Haubold +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Nature CommunicationsAtmospheric entry of asteroids or comets can cause significant damage to Earth. Two international bodies, the International Asteroid Warning Network (IAWN), and the Space Mission Planning Advisory Group (SMPAG) are working on dealing with potential ...
Detlef V. Koschny +2 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source