Results 101 to 110 of about 324,246 (376)

Constrained semi-analytical models of Galactic outflows [PDF]

, 2008
We present semi-analytic models of galactic outflows, constrained by available observations on high redshift star formation and reionization. Galactic outflows are modeled in a manner akin to models of stellar wind blown bubbles. Large scale outflows can
Barkana R., Batchelor G. K., Binney J., Brandenburg A., Chandrasekhar S., Dekel A., Kandaswamy Subramanian, Padmanabhan T., Raghunathan Srianand, Sasaki S., Saumyadip Samui, Zeldovich Y. B.   +11 more
core   +3 more sources

Powerful Outflows and Feedback from Active Galactic Nuclei [PDF]

, 2015
Active Galactic Nuclei (AGN) represent the growth phases of the supermassive black holes in the center of almost every galaxy. Powerful, highly ionized winds, with velocities $\sim 0.1- 0.2c$ are a common feature in X--ray spectra of luminous AGN ...
A. King, K. Pounds
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Net Foreign Direct Investment Development Path of the EU Member States

Ekonomski Vjesnik, 2013
The main objective of this research was to investigate the relationship between net foreign direct investment outflow and economic development on a sample of the European Union (EU) Member States and the Republic of Croatia which is soon to become a full
Sanja Franc
doaj  

The Many Routes to AGN Feedback

Frontiers in Astronomy and Space Sciences, 2017
The energy released by Active Galactic Nuclei (AGN) in the form of radiation, winds, or radio plasma jets, is known to impact on the surrounding interstellar medium. The result of these processes, known as AGN (negative) feedback, is suggested to prevent
Raffaella Morganti, Raffaella Morganti
doaj   +1 more source

Outflows and mass accretion in collapsing dense cores with misaligned rotation axis and magnetic field

, 2010
Outflows and jets are intimately related to the formation of stars, and play an important role in redistributing mass, energy and angular momentum within the dense core and parent cloud.
Anderson, Andrea Ciardi, Appl, Bacciotti, Banerjee, Blandford, Cabrit, Ciardi, Fendt, Ferreira, Ferreira, Fromang, Hartigan, Hennebelle, Hennebelle, Hunter, Kudoh, Lebedev, Lynden-Bell, Machida, Machida, Machida, Matzner, Mellon, Moll, Nakamura, Ouyed, Patrick Hennebelle, Pelletier, Price, Pudritz, Pudritz, Spruit, Teyssier, Uchida, Ustyugova, Wu, Zanni   +37 more
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Production of the entire range of r-process nuclides by black hole accretion disc outflows from neutron star mergers [PDF]

, 2016
We consider $r$-process nucleosynthesis in outflows from black hole accretion discs formed in double neutron star and neutron star -- black hole mergers. These outflows, powered by angular momentum transport processes and nuclear recombination, represent
Meng-Ru Wu, R. Fern'andez, G. Mart'inez-Pinedo, B. Metzger   +3 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Anisotropic AGN Outflows and Enrichment of the Intergalactic Medium

, 2009
We investigate the cosmological-scale influence of outflows driven by AGNs on metal enrichment of the intergalactic medium. AGNs are located in dense cosmological structures which tend to be anisotropic.
Barai, Barai, Barger, Begelman, Bicknell, Blundell, Chartas, Chartas, Choi, Ciotti, Ciotti, Crenshaw, Croston, Das, Dasgupta, Fragile, Furlanetto, Ganguly, Gebhardt, Granato, Grenon, Hickox, Hinshaw, Ho, Ho, Hopkins, Hugo Martel, Joël Germain, Juneau, King, Kormendy, Kronberg, Krongold, Laor, Levine, Mac Low, Magorrian, Marconi, Martel, Martel, Martel, Miller, Murray, Nesvadba, O'Brien, Paramita Barai, Peterson, Pieri, Rafter, Recchi, Rees, Reichard, Richards, Scannapieco, Scannapieco, Schlesinger, Shang, Shankar, Shen, Silk, Springel, Thacker, van Breugel, Wyithe, Yu   +64 more
core   +1 more source