Results 101 to 110 of about 305,999 (243)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Helical Magnetic Fields in the NGC1333 IRAS 4A Protostellar Outflows

, 2016
We present Submillimeter Array (SMA) polarization observations of the CO $J$ = 3--2 line toward the NGC1333 IRAS 4A. The CO Stokes $I$ maps at an angular resolution of $\sim$1$\arcsec$ reveal two bipolar outflows from the binary sources of the NGC 1333 ...
Ching, Tao-Chung, Girart, Josep M., Lai, Shih-Ping, Rao, Ramprasad, Yang, Louis, Zhang, Qizhou   +5 more
core   +1 more source

Tracing outflows in the AGN forbidden region with SINFONI [PDF]

, 2016
AGN driven outflows are invoked in numerical simulations to reproduce several observed properties of local galaxies. The z > 1 epoch is of particular interest as it was during this time that the volume averaged star formation and the accretion rate of ...
D. Kakkad, V. Mainieri, P. Padovani, G. Cresci, B. Husemann, S. Carniani, S. Carniani, S. Carniani, M. Brusa, M. Brusa, A. Lamastra, G. Lanzuisi, G. Lanzuisi, E. Piconcelli, M. Schramm   +14 more
semanticscholar   +1 more source

MODEL OF A DISK-OUTFLOW COUPLED SYSTEM: DISK-OUTFLOW SYMBIOSIS [PDF]

The Thirteenth Marcel Grossmann Meeting, 2015
Several observational evidences and deeper theoretical insights reveal that accretion and outflow/jet are strongly correlated. We model an advective disk-outflow coupled dynamics. We investigate the properties of the disk-outflow surface and how is it dependent on the spin of the black hole.
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Massive molecular outflows and evidence for AGN feedback from CO observations [PDF]

, 2013
We study the properties of massive, galactic-scale outflows of molecular gas and investigate their impact on galaxy evolution. We present new IRAMPdBI CO(1-0) observations of local ultra-luminous infrared galaxies (ULIRGs) and quasar-hosts: a clear ...
C. Cicone, R. Maiolino, E. Sturm, J. Graciá-Carpio, C. Feruglio, R. Neri, S. Aalto, R. Davies, F. Fiore, J. Fischer, S. García-Burillo, E. González-Alfonso, S. Hailey-Dunsheath, E. Piconcelli, S. Veilleux   +14 more
semanticscholar   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Molecules in Bipolar Outflows

, 2012
Bipolar outflows constitute some of the best laboratories to study shock chemistry in the interstellar medium. A number of molecular species have their abundance enhanced by several orders of magnitude in the outflow gas, likely as a combined result of ...
Arce, Bachiller, Bachiller, Bachiller, Bisschop, Bjerkeli, Bontemps, Cernicharo, Codella, Davis, Elitzur, Faure, Flower, Gusdorf, Kristensen, Liseau, Mario Tafalla, Nisini, Nisini, Rafael Bachiller, Rodríguez-Fernández, Rosenthal, Santiago-García, Schöier, Tafalla, Tafalla, Tafalla   +26 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source