Results 121 to 130 of about 322,282 (370)
THE ROLE OF COSMIC-RAY PRESSURE IN ACCELERATING GALACTIC OUTFLOWS [PDF]
, 2016 We study the formation of galactic outflows from supernova (SN) explosions with the moving-mesh code AREPO in a stratified column of gas with a surface density similar to the Milky Way disk at the solar circle.
C. Simpson +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Mass Ejection from the Symbiotic Prototype Z and During its 2006 Outburst
Open Astronomy, 2012 High-resolution spectroscopic observations in the region of the Balmer Hα and Hγ lines of the symbiotic binary Z And were performed during its major eruption in 2006.
Tomov N. A. +2 more
doaj +1 more source
The Nature and Frequency of Outflows from Stars in the Central Orion Nebula Cluster [PDF]
, 2015 Recent Hubble Space Telescope images have allowed the determination with unprecedented accuracy of motions and changes of shocks within the inner Orion Nebula.
Ferland, G. J. +5 more
core +3 more sources
The Astrophysical Journal, 1999 A model is developed for magnetic `propeller'-driven outflows which cause a rapidly rotating magnetized star accreting from a disk to spin-down. Energy and angular momentum lost by the star goes into expelling most of the accreting disk matter.
Lovelace, R. V. E. +2 more
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
PROTOSTELLAR OUTFLOWS AND RADIATIVE FEEDBACK FROM MASSIVE STARS. II. FEEDBACK, STAR-FORMATION EFFICIENCY, AND OUTFLOW BROADENING [PDF]
, 2016 We perform two-dimensional axially symmetric radiation hydrodynamic simulations to assess the impact of outflows and radiative force feedback from massive protostars by varying when the protostellar outflow starts, and to determine the ratio of ejection ...
R. Kuiper, N. Turner, H. Yorke
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Global dynamics of advection-dominated accretion flows with magnetically driven outflow
, 2009 We study the global dynamics of advection-dominated accretion flows (ADAFs) with magnetically driven outflows. A fraction of gases in the accretion flow is accelerated into the outflows, which leads to decreasing of the mass accretion rate in the ...
Armitage +49 more
core +1 more source
A deep Tasman outflow of Pacific waters during the last glacial period [PDF]
, 2022 Torben Struve +4 more
openalex +1 more source