Results 81 to 90 of about 23,619,888 (317)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A Comparison of Outlier Detection Techniques for High-Dimensional Data

open access: yesInternational Journal of Computational Intelligence Systems, 2018
Outlier detection is a hot topic in machine learning. With the newly emerging technologies and diverse applications, the interest of outlier detection is increasing greatly.
Xiaodan Xu   +3 more
doaj   +1 more source

Multi-Level Clustering-Based Outlier’s Detection (MCOD) Using Self-Organizing Maps

open access: yesBig Data and Cognitive Computing, 2020
Outlier detection is critical in many business applications, as it recognizes unusual behaviours to prevent losses and optimize revenue. For example, illegitimate online transactions can be detected based on its pattern with outlier detection.
Menglu Li, Rasha Kashef, Ahmed Ibrahim
doaj   +1 more source

Domain-Agnostic Outlier Ranking Algorithms—A Configurable Pipeline for Facilitating Outlier Detection in Scientific Datasets

open access: yesFrontiers in Astronomy and Space Sciences, 2022
Automatic detection of outliers is universally needed when working with scientific datasets, e.g., for cleaning datasets or flagging novel samples to guide instrument acquisition or scientific analysis.
Hannah R. Kerner   +8 more
doaj   +1 more source

Identification of Outlying Observations with Quantile Regression for Censored Data [PDF]

open access: yes, 2014
Outlying observations, which significantly deviate from other measurements, may distort the conclusions of data analysis. Therefore, identifying outliers is one of the important problems that should be solved to obtain reliable results.
Cho, HyungJun   +2 more
core  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Outlier Detection and Explanation Method Based on FOLOF Algorithm

open access: yesEntropy
Outlier mining constitutes an essential aspect of modern data analytics, focusing on the identification and interpretation of anomalous observations. Conventional density-based local outlier detection methodologies frequently exhibit limitations due to ...
Lei Bai, Jiasheng Wang, Yu Zhou
doaj   +1 more source

Provable Self-Representation Based Outlier Detection in a Union of Subspaces

open access: yes, 2017
Many computer vision tasks involve processing large amounts of data contaminated by outliers, which need to be detected and rejected. While outlier detection methods based on robust statistics have existed for decades, only recently have methods based on
Robinson, Daniel P.   +2 more
core   +1 more source

Effect of adjunctive ranitidine for antipsychotic-induced weight gain: A systematic review of randomized placebo-controlled trials [PDF]

open access: yes, 2017
This study was a meta-analysis of randomized controlled trials (RCTs) of ranitidine as an adjunct for antipsychotic-induced weight gain in patients with schizophrenia.
Chen, Rui   +13 more
core   +3 more sources

Outlier sums for differential gene expression analysis [PDF]

open access: yesBiostatistics, 2006
We propose a method for detecting genes that, in a disease group, exhibit unusually high gene expression in some but not all samples. This can be particularly useful in cancer studies, where mutations that can amplify or turn off gene expression often occur in only a minority of samples.
Robert, Tibshirani, Trevor, Hastie
openaire   +2 more sources

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