Results 61 to 70 of about 190,177 (262)
GTI: a novel algorithm for identifying outlier gene expression profiles from integrated microarray datasets. [PDF]
PLoS ONE, 2011 BACKGROUND: Meta-analysis of gene expression microarray datasets presents significant challenges for statistical analysis. We developed and validated a new bioinformatic method for the identification of genes upregulated in subsets of samples of a given ...
John Patrick Mpindi +13 more
doaj +1 more source
Outlier Identification in Model-Based Cluster Analysis [PDF]
Journal of Classification, 2015 In model-based clustering based on normal-mixture models, a few outlying observations can influence the cluster structure and number. This paper develops a method to identify these, however it does not attempt to identify clusters amidst a large field of noisy observations. We identify outliers as those observations in a cluster with minimal membership
Katie Evans +2 more
openaire +4 more sources
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
A geometric analysis of subspace clustering with outliers
The Annals of Statistics, 2012 This paper considers the problem of clustering a collection of unlabeled data points assumed to lie near a union of lower-dimensional planes. As is common in computer vision or unsupervised learning applications, we do not know in advance how many subspaces there are nor do we have any information about their dimensions.
Soltanolkotabi, Mahdi +1 more
openaire +4 more sources
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
International Journal of Distributed Sensor Networks, 2015 Since the nonstationary distribution of the detected objects is general in the real world, the accurate and efficient outlier detection for data analysis within wireless sensor network (WSN) is a challenge.
Haiqing Yao, Heng Cao, Jin Li
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
CLASSIFICATION OF TASKS OF DATA MINING AND DATA PROCESSING IN THE ECONOMY
Baltic Journal of Economic Studies, 2017 The subject of the paper is methods of classification of data mining and data processing tasks in the economy, as well as their classification characteristics. Methodology.
Aleksey Mints
doaj
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source