Results 101 to 110 of about 6,186,359 (298)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Assessment of the output of primary school fifth grade Koran [PDF]

فصلنامه نوآوری‌های آموزشی, 2013
The aim of this research was evaluation of the output of primary school fifth grade Koran curriculum at the academic year of 1388-1389. The data included test scores on accuracy and speed of reading Koran and textbook of Koran education and also the ...
Mohammad Hasan Mirzā Mohammadi, Abdollāh Afshār, Rasul Shāhrezāyi, Mohtaram Ghobādi   +3 more
doaj  

Specific Features of Estimating Labour Productivity in Railway Transport

Вестник Российского экономического университета имени Г. В. Плеханова, 2019
The article studies the principle methods of estimating labour productivity, such as vector, multi-criteria and multifactor. The author provides their comparative characteristic, which shows vector methods as the most suitable to estimate labour ...
A. O. Batsokin
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Efficiently computing the cyclic output-to-output gain

Systems & Control Letters
The cyclic output-to-output gain is a security metric for control systems. Commonly, it is computed by solving a semi-definite program, which scales badly and inhibits its use for large-scale systems. We propose a method for computing the cyclic output-to-output gain using Hamiltonian matrices, similar to existing methods for the $H_\infty$-norm.
Daniel Arnström, André M.H. Teixeira
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Evaluasi Sistem Informasi Penjualan Kredit dan Piutang Dagang

ComTech, 2011
This study evaluates the implementation of management control and internal controls in application of sales systems information as a basis to support and produce accurate information in decision making. The methods used are bibliography study, interview,
I Gusti Made Karmawan
doaj   +1 more source

MULTIDIMENSIONAL OUTPUT INDICES [PDF]

This abstract describes alternative output aggregates that provide both cross-sectional and temporal comparisons appropriate for the analysis of panel data sets.
Craig, Barbara J., Pardey, Philip G.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

REFORM, ORGANISATION AND CONSOLIDATION OF THE ROMANIAN BANKING SYSTEM [PDF]

Annals of the University of Petrosani: Economics, 2012
Banking system, making the economic environment and the resources it provides, the subsystem consists of macro economic and social. He is in continuous interaction with the economic environment, which takes "input" in various forms - human, financial ...
ION Gr. IONESCU
doaj