Results 81 to 90 of about 2,643,650 (314)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Estimating Output Gaps [PDF]

open access: yes
The output gap, defined as actual less potential output, is an important variable in its own right and as an indicator of incipient changes in inflation.
Gordon de Brouwer
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Potential Output and the Output Gap in Ireland [PDF]

open access: yes
The performance of the Irish economy in recent years has been outstanding. Between 1994 and 2000, Ireland’s economic growth, as measured by the annual percentage change in real GDP (Gross Domestic Product), has expanded at an annual average rate of ...
Slevin, Geraldine
core  

Univariate Potential Output Estimations for Hungary [PDF]

open access: yes
Potential output figures are important ingredients of many macroeconomic models and are routinely applied by policy makers and global agencies. Despite its widespread use, estimation of potential output is at best uncertain and depends heavily on the ...
Zsolt Darvas, Gábor Vadas
core   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The reliability of Canadian output gap estimates [PDF]

open access: yes
Recent work on policy rules under uncertainty have highlighted the impact of output gap measurement errors on economic outcomes and their importance in the formulation of appropriate policy rules.
van Norden, Simon, Cayen, Jean-Philippe
core  

Rating of Iranian Medical Sciences Universities in Education, Based on Efficiency Index [PDF]

open access: yesمجله ایرانی آموزش در علوم پزشکی, 2011
Introduction: Due to the development and the importance of universities of medical sciences in education system in Iran, this study was performed to rate universities of medical sciences in the field of education based on inputs and outputs.
zohre sohrabi   +5 more
doaj  

Competitiveness of the Czech food industry

open access: yesAgricultural Economics (AGRICECON), 2011
The study is engaged in the problems of competitiveness and the performance of the Czech food industry. Both these attributes are evaluated in the framework the domestic manufacturing sector and market, as well as from the point of view of the relations ...
Marie PUTIĆOVÁ, Josef MEZERA
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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