Results 81 to 90 of about 2,643,650 (314)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
The output gap, defined as actual less potential output, is an important variable in its own right and as an indicator of incipient changes in inflation.
Gordon de Brouwer
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Potential Output and the Output Gap in Ireland [PDF]
The performance of the Irish economy in recent years has been outstanding. Between 1994 and 2000, Ireland’s economic growth, as measured by the annual percentage change in real GDP (Gross Domestic Product), has expanded at an annual average rate of ...
Slevin, Geraldine
core
Univariate Potential Output Estimations for Hungary [PDF]
Potential output figures are important ingredients of many macroeconomic models and are routinely applied by policy makers and global agencies. Despite its widespread use, estimation of potential output is at best uncertain and depends heavily on the ...
Zsolt Darvas, Gábor Vadas
core +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The reliability of Canadian output gap estimates [PDF]
Recent work on policy rules under uncertainty have highlighted the impact of output gap measurement errors on economic outcomes and their importance in the formulation of appropriate policy rules.
van Norden, Simon, Cayen, Jean-Philippe
core
Rating of Iranian Medical Sciences Universities in Education, Based on Efficiency Index [PDF]
Introduction: Due to the development and the importance of universities of medical sciences in education system in Iran, this study was performed to rate universities of medical sciences in the field of education based on inputs and outputs.
zohre sohrabi +5 more
doaj
Competitiveness of the Czech food industry
The study is engaged in the problems of competitiveness and the performance of the Czech food industry. Both these attributes are evaluated in the framework the domestic manufacturing sector and market, as well as from the point of view of the relations ...
Marie PUTIĆOVÁ, Josef MEZERA
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

