Results 81 to 90 of about 276,167 (312)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Adaptive output feedback control based on neural networks: application to flexible aircraft control [PDF]

, 2009
One of the major challenges in aeronautical flexible structures control is the uncertain for the non stationary feature of the systems. Transport aircrafts are of unceasingly growing size but are made from increasingly light materials so that their ...
J. Bordeneuve-Guibé, Bako, Laurent, Jeanneau, Matthieu, Bordeneuve-Guibé, Joël, L. Bako, M. Jeanneau   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Delay-dependent output feedback compensators for a class of networked control systems [PDF]

, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Automação e Sistemas, Florianópolis, 2014Sistemas de controle via rede (NCS, do inglês Networked Control Systems) são uma classe ...
Moraes, Vitor Mateus
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

PI output feedback control of differential linear repetitive processes

, 2008
Repetitive processes are characterized by a series of sweeps, termed passes, through a set of dynamics defined over a finite duration known as the pass length.
Rogers, E, Bartlomiej Sulikowski, Eric Rogers, Sulikowski, B, Galkowski, K, Krzysztof Galkowski   +5 more
core   +1 more source

Output Feedback-Based Neural Network Sliding Mode Control for Electro-Hydrostatic Systems with Unknown Uncertainties

Machines
This paper proposes an output feedback-based control for uncertain electro-hydrostatic systems (EHSs) to satisfy high output tracking precision under the influences of unknown mismatched and matched uncertainties and unstructured dynamical behavior.
Tri Dung Dang, Tri Cuong Do, Hoai Vu Anh Truong   +2 more
doaj   +1 more source

Output feedback disturbance rejection control for building structure systems subject seismic excitations

Measurement + Control, 2020
In this paper, the output feedback disturbance rejection control (OFDRC) problem is considered for buildings structures subject seismic excitations.
Qixun Lan, Xiaoguo Zhang, Yajie Li, Jingjing Mu, Weiping Zhu, Huafeng Xu   +5 more
doaj   +1 more source

Destabilization by output feedback

Differential and Integral Equations, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hinrichsen, D., Pritchard, A. J.
openaire   +3 more sources

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source