Results 111 to 120 of about 4,205,611 (298)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The Sustainability of Public Finances in Republic of Moldova Under EU Fiscal Rules
Scientific Annals of Economics and Business, 2016 This paper analyses public finances sustainability in the Republic of Moldova under the European Union fiscal rules, by estimating the structural budget balance indicator using a three steps methodology.
Covalschi Tatiana, Lazăr Sebastian
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Data Revisions and the Output Gap [PDF]
Preliminary and delayed Colombian GDP reports are replaced with optimal in-sample now-casts of "true" GDP figures derived from a model for data revisions.
Juan Manuel Julio
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
THE IMPACT OF THE COMBINATION OF MONETARY AND FISCAL POLICIES ON MACROECONOMIC STABILITY: AN SVAR ANALYSIS OF MENA ECONOMIES (1990 2023) THROUGH THE OUTPUT GAP AND INFLATION [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria EconomieThis research analyses the influence of fiscal and monetary policies (policy mix) on the macroeconomic stability of four countries in the MENA region (Morocco, Tunisia, Algeria, Saudi Arabia) for the period from 1990 to 2023 using an SVAR model.
EL KHATTAB YOUNES , BASSITE IMAD
doaj
Estimating the output gap for the Maltese economy [PDF]
An attempt is made in this paper to arrive at an estimate of the output gap for the Maltese economy on a quarterly and annual basis. Two approaches are adopted, namely the Hodrick-Prescott filter and the aggregate production function method, with their ...
Grech, Aaron George
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Real time estimates of the euro area output gap: reliability and forecasting performance [PDF]
This paper provides evidence on the reliability of euro area real-time output gap estimates. A genuine real-time data set for the euro area is used, including vintages of several sets of euro area output gap estimates available from 1999 to 2006.
Musso, Alberto, Marcellino, Massimiliano
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source