Results 121 to 130 of about 4,205,611 (298)
The Forecasting Performance of Real Time Estimates of the EURO Area Output Gap [PDF]
This paper provides real time evidence on the usefulness of the euro area output gap as a leading indicator for inflation and growth. A genuine real-time data set for the euro area is used, including vintages of several alternative gap estimates.
Alberto Musso, Massimiliano Marcellino
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Double conditioned potential output [PDF]
The central point of this paper is that both - internal and external - equilibria ought to be involved in the estimation of potential output. If only the data on inflation, unemployment rate and wages are used for its evaluation, no certainty exists that
Dobrescu, Emilian
core +2 more sources
STATISTICAL MEASURES OF THE OUTPUT GAP DISTRIBUTION AMONG EUROPEAN COUNTRIES IN THE YEARS 2000–2019
Research on Enterprise in Modern Economy Theory and PracticeBackground and Objective: The concept of full capacity utilisation is central in macroeconomic theory and economic policy. One of the most employed variables is the output gap, which shows the gap between real and potential production.
Paweł Umiński
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Estimating the output gap in times of COVID-19
Latin American Journal of Central BankingWe extend a standard multivariate filter used to estimate the Output Gap (OG) in Chile to account for large economic shocks, such as those observed during the COVID-19 crisis. We propose two methodological extensions. First, we introduce exogenous supply
Luigi Durand, Jorge Alberto Fornero
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
ON THE MOLDOVAN ECONOMY’S POTENTIAL OUTPUT AND OUTPUT GAP: EVIDENCE FROM THE HODRICK-PRESCOTT FILTER
Economy and SociologyThis paper introduces the notion of an economy’s potential output, its output gap and its output gap rate, analyses the properties of the Hodrick-Prescott filter drawing from the studies in the literature, and proceeds to estimate and discuss Moldova’s ...
Apostolos Papaphilippou
doaj +1 more source