Results 51 to 60 of about 7,272,342 (262)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Comparative Study of 10 Wp Solar Panel Performance with Mirror Reflectors at Various Angles

open access: yesJurnal Elkomika
Improving solar panel performance is challenging due to increasing of solar radiation. This study investigates the effect of variations in the angle of the flat mirror reflector on the surface temperature and electrical performance of a 10 Wp ...
BASYARUDDIN ISMAIL HARAHAP   +4 more
doaj   +1 more source

Improving the Misalignment Tolerance of Wireless Power Transfer System for AUV with Solenoid-Dual Combined Planar Magnetic Coupler

open access: yesJournal of Marine Science and Engineering, 2023
In order to solve the problem of power transmission efficiency reduction resulting from misalignment in the Wireless Power Transfer (WPT) system for Autonomous Underwater Vehicle (AUVs), a novel coupling structure with strong tolerance to misalignment is
Haibing Wen   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Micro-Power Generator Based on Two Piezoelectric MFC Films

open access: yesCrystals, 2021
In order to realize the collection of micro or small vibration energy, a micro-power generator based on two piezoelectric Macro Fiber Composite (MFC) films is proposed. The piezoelectric generator consists of a double piezoelectric MFCs type vibrator and
Yongxin Ma   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Buck-boost single-inductor multiple-output (SIMO) high-frequency inverters for medium-power wireless power transfer [PDF]

open access: yes, 2018
In this paper, a non-isolated buck-boost single-inductor multiple-output (SIMO) DC-AC inverter for driving multiple independent high-frequency AC outputs of medium power, is proposed.
Tan, SC, Jin, W, Lee, ATL, Hui, R
core   +1 more source

Technical Characterization of a High-Power Diode Laser at 445 nm for Medical Applications: From Continuous Wave Down to Pulse Durations in the µs-Range

open access: yesApplied Sciences
The technical development of diode lasers with regard to wavelengths, output powers and pulse durations in the order of microseconds is expanding the range of medical applications. The 445 nm wavelength, in particular, offers a promising approach. Such a
Zhaoqun Liu   +3 more
doaj   +1 more source

1 W/mm Output Power Density for H-Terminated Diamond MOSFETs With Al2O3/SiO2 Bi-Layer Passivation at 2 GHz

open access: yesIEEE Journal of the Electron Devices Society, 2021
We have demonstrated a novel method of depositing ALD-Al2O3/PECVD-SiO2 bi-layer dielectric to passive the surface channels of the hydrogen-terminated diamond (H-diamond).
Xinxin Yu   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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