Results 71 to 80 of about 676,492 (269)

Effect of Temperature on Electrical Parameters of Phosphorous Spin–on Diffusion of Polysilicon Solar Cells [PDF]

Journal of Renewable Energy and Environment, 2017
Effects of temperature on electrical parameters of polysilicon solar cells, fabricated using the phosphorous spin-on diffusion technique, have been studied.
Siamak Azimi-Nam, Foad Farhani
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Harvesting wind gust energy with small and medium wind turbines using a bidirectional control strategy

The Journal of Engineering, 2019
Wind energy is an important renewable source with a stochastic nature. To capture this energy, variable speed generators are installed in wind towers and different maximum power point (MPP) tracking (MPPT) strategies have been developed in literature to ...
Milad Sajadi, Jeroen D. M. De Kooning, Lieven Vandevelde, Guillaume Crevecoeur   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

A Transformerless AC-AC Converter with Improved Power Quality Employed to Step-Down Power Frequency at Output

, 2022
Variable voltage and frequency are required to govern the torque-speed characteristics of many industrial drive systems. Traditionally, this is achieved with a power converting system implemented with multistage converters.
Ghulam Abbas, Abdul Rehman Yasin, Ahmad Aziz Al-Ahmadi, Mohsin Jamil, Naveed Ashraf, Nasim Ullah, Ahmed Bilal Awan   +6 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

GaN-based MIS HEMT with SiAlN gate dielectric achieving over 70% PAE and 10 W mm−1 at 8 GHz

Applied Physics Express
We achieved a simultaneous record-high power-added efficiency (PAE) of 71.4% and an output power density of 10.4 W mm ^−1 at 8 GHz in an AlGaN/GaN metal-insulator-semiconductor (MIS) high-electron-mobility transistor (HEMT) on a free-standing GaN ...
Yuichi Minoura, Atsushi Yamada, Kenji Saito, Norikazu Nakamura, Toshihiro Ohki   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Fiber MOPAs with high control and high power [PDF]

, 2008
High power fiber sources have reached several kilowatts of output power, and are now leading contenders for many applications. Important attractions include control, efficiency, manufacturability, and reliability.
M. S. Z. Abidin, J.-N. Maran, Nilsson, J., Abidin, M.S.Z., Maran, J.-N., Codemard, C.A., Y. Jeong, Dupriez, P., Richardson, D.J., Farrell, C., Yoo, S., S. Yoo, Payne, D.N., Jeong, Y., J. Nilsson, J. Ji, J. K. Sahu, Ji, J., C. Farrell, D. J. Richardson, C. A. Codemard, P. Dupriez, Sahu, J.K., D. N. Payne   +23 more
core   +1 more source