Results 81 to 90 of about 385,031 (304)

Acetylcholine-treated murine dendritic cells promote inflammatory lung injury [PDF]

open access: yes, 2019
In recent years a non-neuronal cholinergic system has been described in immune cells, which is often usually activated during the course of inflammatory processes. To date, it is known that Acetylcholine (ACh), a neurotransmitter extensively expressed in
Alcain, Julieta María   +8 more
core   +1 more source

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou   +10 more
wiley   +1 more source

Actual problems of municipal cleaner’s waste waters [PDF]

open access: yesActa Montanistica Slovaca, 2000
In paper are evaluated social and economical changes in water economy with emphasis on complex evaluation of municipal cleaner’s waste waters with respect of legislative, position of ownerskip relationskips and financial security of public experiences of
Konko¾ová Patrícia
doaj  

Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally

open access: yesAntibodies, 2016
Nanoparticles (NPs) are increasingly being used for drug delivery, as well as antigen carriers and immunostimulants for the purpose of developing vaccines. In this work, we examined how intranasal (i.n.) priming followed by i.n.
Savannah E. Howe   +2 more
doaj   +1 more source

Hubungan Hipertiroid dengan Aktivitas Kerja pada Wanita Usia Subur [PDF]

open access: yes, 2007
Background: Based on disorder mapping due to Iodine deficiency in 1998 and 2003, elimination of Iodine deficiency in household by consuming minimally 90 percent Iodine salt and giving Iodine oil capsule to fertile women in endemic Iodine deficiency ...
Supadmi, Ova Emilia, Hari Kusnanto, Sri
core  

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li   +8 more
wiley   +1 more source

Platelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells

open access: yesFrontiers in Immunology, 2018
Delivery of gene therapy as well as of biologic therapeutics is often hampered by the immune response of the subject receiving the therapy. We have reported that effective gene therapy for hemophilia utilizing platelets as a delivery vehicle engenders ...
Xiaofeng Luo   +17 more
doaj   +1 more source

Maturation, Spawning Period, and Fecundity of the White Crappie, Pomoxis annularis Rafinesque, in Beaver Reservoir, Arkansas [PDF]

open access: yes, 1981
Gonosomatic indices and ovum diameter frequency distributions showed that the Beaver Reservoir white crappie spawns from late April through May. During the spawning season females release eggs more than once.
Kilambi, Raj V., Thomas, Janet L.
core   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Bisphenol A Exacerbates Allergic Inflammation in an Ovalbumin-Induced Mouse Model of Allergic Rhinitis

open access: yesJournal of Immunology Research, 2020
Purpose. Bisphenol A (BPA) is found in many plastic products and is thus a common environmental endocrine disruptor. Plastic-related health problems, including allergic diseases, are attracting increasing attention. However, few experimental studies have
Yunxiu Wang   +5 more
doaj   +1 more source

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