Results 101 to 110 of about 3,449,000 (279)

Da Vinci Single-Port surgery in an obese woman affected by endometrial cancer

open access: yesFacts, Views & Vision in ObGyn
Background: Minimally invasive surgery in obese patients is advantageous in terms of postoperative recovery and estimated blood loss. In literature several retrospective studies comparing robot-assisted and laparoscopic surgery are present, while a ...
Benedetta Alberghetti   +9 more
doaj   +1 more source

Bevacizumab in Ovarian Cancer

open access: yesNew England Journal of Medicine, 2012
N Engl J ...
Mehmet S, Copur   +2 more
openaire   +5 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ovarian cancer serum biomarker discovery using proteomics [PDF]

open access: yes, 2008
Ovarian cancer is a lethal gynaecological malignancy which is known as the silent killer. It has a poor prognosis due to the lack of major symptoms in early stage disease and hence its late detection.
Kabir, M.
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models

open access: yesSTAR Protocols
Summary: Three-dimensional (3D) ex vivo cultures allow the study of cancer progression and drug resistance mechanisms. Here, we present a protocol for measuring on-target drug sensitivity in a scaffold-free 3D culture system through quantification of ...
Kathrin B. Labrosse   +7 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Chemotherapy-induced dynamic gene expression changes in vivo are prognostic in ovarian cancer [PDF]

open access: yes, 2014
This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7-Directorate-General for Research and Innovation of the European Commission (EU HEALTH-F4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
A Koussounadis   +11 more
core   +1 more source

Single-Cell Analysis Links C7+ Cancer-Associated Fibroblasts with Incomplete Resection in Platinum-Sensitive Relapsed Ovarian Cancer

open access: yesBiomedicines
Background/Objectives: Achieving complete resection (R0) during secondary cytoreduction (SCR) is a pivotal prognostic factor for patients with platinum-sensitive relapsed ovarian cancer (PSROC).
Longxia Li   +9 more
doaj   +1 more source

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