Results 181 to 190 of about 5,260,709 (398)

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Fertility-Sparing Surgery in Early Epithelial Ovarian Cancer: A Viable Option?

Obstetrics and Gynecology International, 2012
Epithelial ovarian cancer (EOC) continues to represent one of the most lethal conditions in women in the western countries. With the shifting of childbearing towards higher age, EOC increasingly affects women with active childbearing wish, resulting in ...
Christina Fotopoulou, Ioana Braicu, Jalid Sehouli   +2 more
doaj   +1 more source

Tumour antigenicity in ovarian cancer [PDF]

, 1975
L Levin, J E McHardy, O. M. Curling, C. N. Hudson   +3 more
openalex   +1 more source

Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Despite initial responsiveness to chemotherapy, the overwhelming majority of advanced ovarian cancer patients relapse with resistant disease. Thus, developing more effective strategies for ovarian cancer treatment is a high clinical priority.
Yanxia Zhao, Jing Cao, A. Melamed, Michael J. Worley, A. Gockley, Dennis Jones, H. Nia, Yanling Zhang, T. Stylianopoulos, A. Kumar, Fotios Mpekris, Meenal Datta, Yao Sun, Limeng Wu, Xing Gao, O. Yeku, M. D. del Carmen, D. Spriggs, R. Jain, Lei Xu   +19 more
semanticscholar   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy

Vaccines, 2016
Genomic destabilizers, such as radiation and chemotherapy, and epigenetic modifiers are used for the treatment of cancer due to their apoptotic effects on the aberrant cells.
Jessica Ann Chacon, Keith Schutsky, Daniel J. Powell   +2 more
doaj   +1 more source

Cell cycle changes in ovarian cancer after arabinosylcytosine [PDF]

, 1974
Patrick F. Sheehy, Jerrold Fried, Rodger J. Winn, Bayard D. Clarkson   +3 more
openalex   +1 more source

ALKBH5 inhibited autophagy of epithelial ovarian cancer through miR-7 and BCL-2

Journal of experimental & clinical cancer research : CR, 2019
ALKBH5 regulated the malignant behavior of breast cancer and glioblastoma. However, the expression and function of ALKBH5 in epithelial ovarian cancer have not yet been determined.
Hongtao Zhu, Xiaoling Gan, Xingwei Jiang, Shuai Diao, Huan Wu, Jianguo Hu   +5 more
semanticscholar   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires, Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond   +4 more
wiley   +1 more source

Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer

Cells, 2019
Detection of epithelial ovarian cancer (EOC) poses a critical medical challenge. However, novel biomarkers for diagnosis remain to be discovered. Therefore, innovative approaches are of the utmost importance for patient outcome.
Hagen Kulbe, Raik Otto, Silvia Darb-Esfahani, Hedwig Lammert, Salem Abobaker, Gabriele Welsch, Radoslav Chekerov, Reinhold Schäfer, Duska Dragun, Michael Hummel, Ulf Leser, Jalid Sehouli, Elena Ioana Braicu   +12 more
doaj   +1 more source