Results 191 to 200 of about 5,337,944 (374)

Chemotherapy of ovarian cancer directed by the human tumor stem cell assay [PDF]

, 1981
David S. Alberts, H. -S. George Chen, Sydney E. Salmon, Earl A. Surwit, Laurie Young, Thomas E. Moon, Frank L. Meyskens   +6 more
openalex   +1 more source

TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Intraperitoneal administration of immunogenic Toll‐like receptor agonist‐modified mesoporous silica nanoparticles leads to rapid internalization by ascites myeloid cells with trafficking to fat‐associated lymphoid clusters. Activation of myeloid cells counters suppressive immune mechanisms associated with peritoneal metastasis, leading to regional and ...
Ben Marwedel, Henning De May, Lauren Anderson, Lorél Y. Medina, Ellie Kennedy, Erica Flores, John O'Rourke, Marian Olewine, Irina Lagutina, Lillian Fitzpatrick, Fred Shultz, Donna F. Kusewitt, Eric Bartee, Sarah Adams, Achraf Noureddine, Rita E. Serda   +15 more
wiley   +1 more source

Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting

Advanced Healthcare Materials, EarlyView.
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari, Mahdieh Shokrollahi Barough, Amir Seyfoori, Mahmood Razzaghi, Joel Alexander Ninan, Aidan B. P. Murray, Mahmoud Salkhordeh, Yuan Tan, Shirley H. J. Mei, Mohsen Akbari   +9 more
wiley   +1 more source

Targeting CCNE1 amplified ovarian and endometrial cancers by combined inhibition of PKMYT1 and ATR

Nature Communications
Ovarian cancers (OVCAs) and endometrial cancers (EMCAs) with CCNE1-amplification are often resistant to standard treatment and represent an unmet clinical need.
Haineng Xu, Erin George, David Gallo, Sergey Medvedev, Xiaolei Wang, Arindam Datta, Rosie Kryczka, Marc L. Hyer, Jimmy Fourtounis, Rino Stocco, Elia Aguado-Fraile, Adam Petrone, Shou Yun Yin, Ariya Shiwram, Fang Liu, Matthew Anderson, Hyoung Kim, Roger A. Greenberg, C. Gary Marshall, Fiona Simpkins   +19 more
doaj   +1 more source

Ovarian carcinosarcoma is highly aggressive compared to other ovarian cancer histotypes

Frontiers in Oncology
BackgroundOvarian carcinosarcoma (OCS) is an unusual ovarian cancer type characterized by distinct carcinomatous and sarcomatous components. OCS has been excluded from many of the pan-histotype studies of ovarian carcinoma, limiting our understanding of ...
Iona McFarlane, Joanna M. Porter, Elizabeth Brownsell, Nidal Ghaoui, Kathryn C. Connolly, C. Simon Herrington, Robert L. Hollis   +6 more
doaj   +1 more source

Mononuclear-cell infiltration in ovarian cancer. II. Immune function of tumour and ascites-derived inflammatory cells [PDF]

, 1982
Stephen Haskill, Hillel S. Koren, S Becker, Wesley C. Fowler, Leslie Walton   +4 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Treatment of advanced ovarian cancer with sequential combination chemotherapy [PDF]

, 1987
Thomas W. Griffin, RICHARD A. HUNTER, Andrew I. Cederbaum, Won K. Tak, Allen Ward, Joel H. Schwartz, Thomas F. Halpin, Gary M. Strauss, Rowland N. Meyer, Marcia K. Liepman, Harry L. Greene, Mary E. Costanza   +11 more
openalex   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

Advanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak, Edith Coonen, Ron van Golde, Erik Vrij   +3 more
wiley   +1 more source

Tumour-associated immune responses and isolated carcinoembryonic antigen and alpha feto-protein levels related to survival in ovarian cancer patients

, 1976
L Levin, J E McHardy, T A Poulton, O. M. Curling, M. J. Kitau, Alan Nevill, C. N. Hudson   +6 more
openalex   +2 more sources